223508-60-9Relevant academic research and scientific papers
Synthesis of Broparestrol using Palladium-Catalyzed Cross-coupling
Al-Hassan, Mohammed I.
, p. 119 - 122 (1987)
The synthesis of broparestrol, a biologically active tetrasubstituted olefin used in dermatology, was achieved via palladium-catalyzed cross-coupling to form a C-C bond followed by bromination.Broparestrol (a cis-trans mixture of α-bromo-α,β-diphenyl-β-(p
Conversion of Stilbene to trisubstituted Olefins
Al-Hassan, Mohammed I.
, p. 463 - 472 (2007/10/02)
Determination of stereochemistry of bromination-dehydrobromination of both cis and trans-stilbene has been achieved.Coupling of the resulting vinyl bromides with alkyl or aryl groups have been done.The coupling products could serve as intermediates for the synthesis of biologically active tetrasubstituted olefins.
