223563-61-9 Usage
Description
(5-(thiophen-3-yl)pyridin-3-yl)methanol is a chemical compound characterized by a molecular formula C13H11NO2S. It features a pyridine ring that is substituted with a thienyl group and a hydroxymethyl group, which endows it with unique structural features and potential pharmacological activities. (5-(thiophen-3-yl)pyridin-3-yl)methanol is recognized for its role as a building block in the synthesis of pharmaceuticals and other organic compounds, making it a valuable asset in medicinal chemistry and drug discovery.
Uses
Used in Pharmaceutical Synthesis:
(5-(thiophen-3-yl)pyridin-3-yl)methanol is used as a key building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structural features allow it to be incorporated into the development of new drugs, potentially leading to the discovery of novel therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (5-(thiophen-3-yl)pyridin-3-yl)methanol is utilized as a versatile reagent for the synthesis of functional materials with potential applications in drug discovery. Its structural properties make it a promising candidate for the design and development of new pharmaceuticals with improved efficacy and selectivity.
Used in Drug Discovery:
(5-(thiophen-3-yl)pyridin-3-yl)methanol is employed as a starting material in drug discovery processes, where its structural features can be exploited to create new compounds with potential therapeutic benefits. Its use in this context is driven by the need for innovative and effective treatments in various medical fields.
Used in Material Science:
In material science, (5-(thiophen-3-yl)pyridin-3-yl)methanol is used as a reagent for the synthesis of various functional materials. Its potential applications in this field are broad, as it can contribute to the development of advanced materials with specific properties for use in different industries.
Further studies on the properties and applications of (5-(thiophen-3-yl)pyridin-3-yl)methanol are necessary to fully explore its potential in scientific and industrial areas, ensuring that its benefits are maximized for the advancement of various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 223563-61-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,5,6 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 223563-61:
(8*2)+(7*2)+(6*3)+(5*5)+(4*6)+(3*3)+(2*6)+(1*1)=119
119 % 10 = 9
So 223563-61-9 is a valid CAS Registry Number.
223563-61-9Relevant articles and documents
Quadruplex-interactive agents as telomerase inhibitors: Synthesis of porphyrins and structure-activity relationship for the inhibition of telomerase
Shi,Wheelhouse,Sun,Hurley
, p. 4509 - 4523 (2007/10/03)
The cationic porphyrin 5,10,15,20-tetra-(N-methyl-4-pyridyl)porphyrin (TMPyP4) binds to quadruplex DNA and is thereby an inhibitor of human telomerase (Wheelhouse et al. J. Am. Chem. Soc. 1998, 120, 3261-3262). Herein the synthesis and telomerase-inhibiting activity of a wide range of analogues of TMPyP4 are reported, from which rules for a structure-activity relationship (SAR) have been discerned: (1) stacking interactions are critical for telomerase inhibition, (2) positively charged substituents are important but may be interchanged and combined with hydrogen-bonding groups, and (3) substitution is tolerated only on the meso positions of the porphyrin ring, and the bulk of the substituents should be matched to the width of the grooves in which they putatively lie. This SAR is consistent with a model presented for the complexation of TMPyP4 with human telomeric quadruplex DNA.
