22359-67-7Relevant academic research and scientific papers
Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate
Guo, Tao,Xia, Rongjiao,Liu, Tingting,Peng, Feng,Tang, Xuemei,Zhou, Qing,Luo, Hui,Xue, Wei
, (2020/03/13)
A series of novel chalcone malonate derivatives were synthesized and their antibacterial and antiviral activities were evaluated. All target compounds were characterized by spectral data. The results of antimicrobial bioassay showed that one compound (die
Investigating the Anticancer Activity of Isatin/Dihydropyrazole Hybrids
Meleddu, Rita,Petrikaite, Vilma,Distinto, Simona,Arridu, Antonella,Angius, Rossella,Serusi, Lorenzo,?karnulyt?, Laura,Endriulaityt?, Ugn?,Pa?kevi?iūt?, Migl?,Cottiglia, Filippo,Gaspari, Marco,Taverna, Domenico,Deplano, Serenella,Fois, Benedetta,Maccioni, Elias
supporting information, p. 571 - 576 (2019/04/25)
A series of isatin-dihydropyrazole hybrids have been synthesized in order to assess their potential as anticancer agents. In particular, 12 compounds were evaluated for their antiproliferative activity toward A549, IGR39, U87, MDA-MB-231, MCF-7, BT474, Bx
Effect of ring A and ring B substitution on the cytotoxic potential of pyrazole tethered chalcones
Nepali, Kunal,Kadian, Kanika,Ojha, Ritu,Dhiman, Rajni,Garg, Atul,Singh, Gagandip,Buddhiraja, Abhishek,Bedi, Preet Mohinder Singh,Dhar, Kanaya Lal
, p. 2990 - 2997 (2012/10/29)
Chalcone is an aromatic ketone that forms the central core for a variety of important biological compounds, which are collectively known as chalcones. The cytotoxic potential of chalcones which consists of C6-C 3-C6 units gets enhanced by the incorporation of pyrazole ring as proved by our earlier studies. Thus in the present work, pyrazoles of chalcones with ring A substituted by furan, naphthalene and variety of substituted phenyl rings has been prepared and evaluated for in vitro cytotoxic activity against PC-3, OVCAR, IMR-32, HEP-2 human cancer cell lines. Springer Science+Business Media, LLC 2011.
Tetrachlorosilane-zinc chloride as a new potent binary reagent for one-pot, three-component synthesis of mannich-type products
Badawy, Doria S.,Abdel-Galil, Ebrahim,Kandeel, Ezzat M.,Basyouni, Wahid M.,Khatab, Tamer K.
experimental part, p. 2799 - 2812 (2010/04/03)
A combination of tetrachlorosilane and zinc chloride in dichloromethane as an efficient and ambient binary reagent to promote a one-pot amidoalkylation reaction of enolizable ketones, aromatic aldehydes with acetonitriles, or benzonitrile have been develo
Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines
Azarifar, Davood,Ghasemnejad, Hassan
, p. 642 - 648 (2007/10/03)
Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields,
