223720-86-3

Basic information

• Product Name: 4-chloro-5-(2-pyrimidinylsulfanyl)-3(2H)-pyridazinone
• Synonyms: 4-chloro-5-(2-pyrimidinylsulfanyl)-3(2H)-pyridazinone
• CAS NO: 223720-86-3
• Molecular Formula: C8H5ClN4OS
• Molecular Weight: 240.6695
• Mol File: 223720-86-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-5-(2-pyrimidinylsulfanyl)-3(2H)-pyridazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-5-(2-pyrimidinylsulfanyl)-3(2H)-pyridazinone(223720-86-3)
• EPA Substance Registry System: 4-chloro-5-(2-pyrimidinylsulfanyl)-3(2H)-pyridazinone(223720-86-3)

Safety Data

• Hazardous Substances Data: 223720-86-3(Hazardous Substances Data)

Upstream product

• 932-22-9 4,5-dichloro-2H-pyridazin-3-one 
• 131242-36-9 2-sulfanylpyrimidine 
• 51355-97-6 4,5-dichloro-2-(hydroxymethyl)pyridazin-3(2H)-one 
• 231613-46-0 acetic acid 5-chloro-6-oxo-4-(pyrimidin-2-ylsulfanyl)-6H-pyridazin-1-ylmethyl ester 

Relevant articles and documents

Direct functionalization of 4,5-dichloropyridazin-6-one

Direct functionalization of 4,5-dichloropyridazin-6-one with some nucleophiles in seven solvents gave regioselectively 5-halo- 4-substituted-pyridazin-6-ones as main product. Reaction of 4,5- dichloropyridazin-6-one with 2-mercaptopyrimidine (2 equivalents) also afforded 4,5-di(pyrimidin-2-ylsulfanyl)pyridazin-6-one as the main product.

Retro-ene reaction. V. Functionalization of 4,5-dihalopyridazin-6-ones using 1-hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O ene- adducts

Functionalization of 1-hydroxymethyl-4,5-dihalopyridazin-6-ones via a retro-ene reaction with some nucleophiles gave regioselectively only 5-halo- 4-substitutedpyridazin-6-ones.