223751-40-4

Upstream product

• 304859-87-8 (1'S)-2-Bromo-3,4-dimethoxy-5-(1',2',2'-trimethylcyclopentyl)benzaldehyde 
• 223751-39-1 (R)-4-(2,3-dimethoxy-5-methylphenyl)-4,5,5-trimethylcyclopent-2-enone 
• 185967-11-7 (1'S)-3,4-dihydroxy-5-(1,2,2-trimethylcyclopentyl)benzaldehyde 
• 37987-21-6 4-hydroxy-3-iodo-5-methoxybenzyl alcohol 
• 304865-25-6 (1R,2S)-2-(2',3'-dimethoxy-5'-methylphenyl)-1,2-dimethylcyclopentylmethyl alcohol 
• 304865-24-5 (1R,2R)-2-(2',3'-dimethoxy-5'-methylphenyl)-1,2-dimethylcyclopentyl-1-carbaldehyde 
• 223751-48-2 (1'S)-1-bromo-2,3-dimethoxy-6-methyl-4-(1',2',2'-trimethylcyclopentyl)benzene 
• 222022-93-7 (1'S)-1,2-dimethoxy-5-methyl-3-(1',2',2'-trimethylcyclopentyl)benzene 
• 304859-86-7 (1'S)-2-bromo-3,4-dihydroxy-5-(1',2',2'-trimethylcyclopentyl)benzaldehyde 
• 304859-77-6 (1'S,2'R)-6-(2'-hydroxymethyl-1',2'-dimethylcyclopentyl)-2-methoxy-4-methylphenol 
• 304859-73-2 (rac)-2'-iodo-6'-methoxy-4'-methylphenyl 1,2-dimethylcyclopent-2-enoate 
• 304859-75-4 (3aS,9bS)-6-Methoxy-3a,8,9b-trimethyl-1,2,3,3a,4,9b-hexahydro-cyclopenta[c]chromen-4-ol 
• 304859-76-5 (3aR,9bR)-cyclopentyl[d]-3a,9bH-6-methoxy-cis-(3a,9b),8-trimethylcoumarin 
• 222022-92-6 (1'S)-3,4-dimethoxy-5-(1',2',2'-trimethylcyclopentyl)benzyl alcohol 

Downstream Products

• 304859-79-8 (1''S,1'''S)-[2'-methoxy-5'-methyl-3'-(1''',2''',2'''-trimethylcyclopentyl)-phenyl] 2-bromo-3,4-dimethoxy-5-(1'',2'',2''-trimethylcyclopentyl)benzoate 

Relevant academic research and scientific papers

Nondynamic and dynamic kinetic resolution of lactones with stereogenic centers and axes: Stereoselective total synthesis of herbertenediol and mastigophorenes A and B

The stereoselective total synthesis of the sesquiterpene herbertenediol (3) and of its naturally occurring dimers, mastigophorenes A [(P)-1] and B [(M)-1], is described. Following the 'lactone concept', the configuration at the biaryl axis was atropo-dive

Total syntheses of (-)-herbertenediol, (-)-mastigophorene A, and (-)- mastigophorene B. Combined utility of chiral bicyclic lactams and chiral aryl oxazolines

A nonracemic bicyclic lactam has been used to construct a chiral cyclopentane containing vicinal quaternary carbon centers in optically pure form, which is common to all of the title compounds. An oxazoline-mediated asymmetric Ullmann coupling was then utilized to establish chirality about the biaryl axis of mastigophorenes A and B. Through the course of this synthesis, it was clearly demonstrated that smaller chiral auxiliaries lead to higher levels of atroposelection, a previously unknown phenomenon of the asymmetric Ullmann coupling.