223769-07-1

Upstream product

• 201230-82-2 carbon monoxide 
• 2930-05-4 (S)-benzyl glycidyl ether 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 261159-47-1 (4S)-4-(benzyloxymethyl)-oxetan-2-one 
• 112348-04-6 ethyl (S)-4-benzyloxy-3-hydroxybutanoate 

Downstream Products

• 700816-60-0 ((2R,4S,6S)-4-Benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-acetic acid ethyl ester 
• 700816-58-6 (2S,4R)-1,4-Bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-pentan-2-ol 
• 700816-59-7 (E)-3-((1S,3R)-3-Benzyloxy-1-benzyloxymethyl-4-bromo-butoxy)-acrylic acid ethyl ester 
• 632357-74-5 (2S,4R)-1-Benzyloxy-5-methyl-hex-5-ene-2,4-diol 
• 398516-79-5 (E)-3-((1S,3R)-1-Benzyloxymethyl-3-hydroxy-4-methyl-pent-4-enyloxy)-acrylic acid ethyl ester 
• 398516-77-3 (2S,4R)-1-Benzyloxy-4-(4-methoxy-benzyloxy)-5-methyl-hex-5-en-2-ol 
• 632357-73-4 2,2-Dimethyl-propionic acid 2-((2S,3R,4R,6S)-6-benzyloxymethyl-4-hydroxy-3-hydroxymethyl-3-methyl-tetrahydro-pyran-2-yl)-ethyl ester 
• 398516-80-8 ((4aS,5S,7S,8aR)-7-Benzyloxymethyl-2,2,4a-trimethyl-hexahydro-1,6-dioxa-2-sila-naphthalen-5-yl)-acetic acid ethyl ester 
• 632357-43-8 2,2-Dimethyl-propionic acid 2-((4aS,5S,7S,8aR)-7-benzyloxymethyl-2,2,4a-trimethyl-tetrahydro-pyrano[4,3-d][1,3]dioxin-5-yl)-ethyl ester 
• 398516-81-9 2,2-Dimethyl-propionic acid 2-[(2S,3R,4R,6S)-6-benzyloxymethyl-4-hydroxy-3-(2-hydroxy-ethyl)-3-methyl-tetrahydro-pyran-2-yl]-ethyl ester 
• 632357-75-6 2,2-Dimethyl-propionic acid 2-((4aS,5S,7S,8aR)-7-benzyloxymethyl-2,2,4a-trimethyl-hexahydro-1,6-dioxa-2-sila-naphthalen-5-yl)-ethyl ester 
• 632357-77-8 2,2-Dimethyl-propionic acid 2-[(2S,3S,4R,6S)-6-benzyloxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-3-vinyl-tetrahydro-pyran-2-yl]-ethyl ester 
• 398516-85-3 2,2-Dimethyl-propionic acid 2-[(2S,3S,4R,6S)-6-benzyloxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-3-hydroxymethyl-3-methyl-tetrahydro-pyran-2-yl]-ethyl ester 

Relevant academic research and scientific papers

Synthesis of anti-l,3-Diols through RuCl3/PPh3-Mediated Hydrogenation of β-Hydroxy Ketones: An alternative to organoboron reagents

Hydrogenation of enantioenriched β-hydroxy ketones promoted by the catalyst generated in situ from commercially available and inexpensive RuCl 3 and PPh3 under hydrogen pressure allowed the efficient preparation of a variety of anti1

Synthesis and evaluation of lasonolide a analogues

Homolasonolide A and 10-desmethyllasonolide A are biologically less active than lasonolide A. The ethyl ester analogue of lasonolide A exhibited higher activity than the parent compound in some biological test.

Lasonolide A: Structural revision and total synthesis

The proposed structure of lasonolide A was synthesized employing radical cyclization reactions of β-alkoxyacrylates for preparation of the tetrahydropyranyl units A and B, but the spectroscopic data did not match those of the natural product. Both enantio

Divergent reaction pathways in amine additions to β-lactone electrophiles. An application to β-peptide synthesis

β-Lactone electrophiles are subject to regioselective addition-elimination (AE) or SN2 ring opening with various nitrogen-based nucleophiles. Primary and secondary amines promote AE ring opening to deliver products that are the functional equiv