22378-46-7Relevant academic research and scientific papers
Biomimetic Asymmetric Reduction of Quinazolinones with Chiral and Regenerable NAD(P)H Models
Zhao, Zi-Biao,Li, Xiang,Wu, Bo,Zhou, Yong-Gui
, p. 714 - 718 (2020)
A facile approach to chiral dihydroquinazolinone derivatives has been described via biomimetic asymmetric reduction of quinazolinones with chiral and regenerable NAD(P)H models. The utility of this method was demonstrated by a concise synthesis of the bromodomain protein divalent inhibitor.
