22389-04-4

Upstream product

• 66065-95-0 1-deamino-1-epi-hydroxysisomicin 
• 140390-53-0 (1R,2R,3R,4S,5R)-5-Benzyloxyamino-cyclohexane-1,2,3,4-tetraol 
• 6207-30-3 2,3:4,5-di-O-isopropylidene-D-glucose diethyl dithioacetal 
• 66065-86-9 3,2',6'-tri-N-acetylsisomicin 
• 66065-86-9 N-[(1S,2R,3R,4S)-2-[(2S,3R)-3-Acetylamino-6-(acetylamino-methyl)-3,4-dihydro-2H-pyran-2-yloxy]-5-amino-4-((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-3-hydroxy-cyclohexyl]-acetamide 
• 66065-91-6 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin 
• 66567-31-5 N-[(1S,2R,3S,4S)-2-[(2S,3R)-3-Acetylamino-6-(acetylamino-methyl)-3,4-dihydro-2H-pyran-2-yloxy]-4-((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-5-ethylamino-3-hydroxy-cyclohexyl]-acetamide 
• 140390-52-9 O-Benzyl-N-((3aS,4R,5aR,8aR,8bR)-2,2,7,7-tetramethyl-hexahydro-benzo[1,2-d;3,4-d']bis[1,3]dioxol-4-yl)-hydroxylamine 
• 140390-42-7 (4R,5S,4'S,5'S)-5'-Bromomethyl-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-carbaldehyde O-benzyl-oxime 

Downstream Products

• 6216-28-0 Pentaacetyl-3-desoxy-myo-inosamin-⁽⁴⁾ 

Relevant academic research and scientific papers

6-Exo Free Radical Cyclization of Acyclic Carbohydrate Intermediates: A New Synthetic Route to Enantiomerically Pure Polyhydroxylated Cyclohexane Derivatives

The 6-exo free radical cyclization of conveniently functionalized acyclic carbohydrate derivatives is a new and efficient method for the asymmetric synthesis of polyhydroxylated cyclohexane compounds (aminocyclitols, pseudosugars).The scope and versatilit

Semisynthetic Aminoglycoside Antibacterials. Part 9. Synthesis of Novel 1- and 3-Substituted and 1- and 3-epi-Substituted Derivatives of Sisomicin and Gentamicin from the 1- and 3-Oxo-derivatives

The conversion of selectively protected gentamicin and sisomicin derivatives into the 1- and 3-oxo-compounds by reaction with 3,5-di-t-butyl-1,2-benzoquinone is described.By application of suitable reductive techniques these oxo-aminoglucosides have been converted into novel 1- and 3-epi-, 1- and 3-deamino-1- and -3-hydroxy-, 1- and 3-deamino-1- and -3-epi-hydroxy, and 1-deamino-derivatives.A study of the 13C n.m.r. parameters of the 1-epi- and 1-deamino-derivatives has led to the assignment of novel solution conformations for these new aminoglycosides.