66065-91-6

Basic information

• Product Name: 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin
• Synonyms: 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin
• CAS NO: 66065-91-6
• Molecular Weight: 572.613
• Mol File: 66065-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin(CAS DataBase Reference)
• NIST Chemistry Reference: 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin(66065-91-6)
• EPA Substance Registry System: 3,2',6'-tri-N-acetyl-1-deamino-1-oxosisomicin(66065-91-6)

Safety Data

• Hazardous Substances Data: 66065-91-6(Hazardous Substances Data)

Upstream product

• 66065-86-9 3,2',6'-tri-N-acetylsisomicin 

Downstream Products

• 67591-15-5 1-epi-N-(3-dimethylaminopropyl)sisomicin 
• 67591-15-5 1-N-(3-dimethylaminopropyl)sisomicin 
• 67650-39-9 1-epi-N-ethylsisomicin 
• 56391-56-1 netilmicin 
• 66065-95-0 1-deamino-1-epi-hydroxysisomicin 
• 66065-95-0 1-deamino-1-hydroxysisomicin 
• 67650-38-8 1-epi-sisomicin 
• 59711-84-1 1-epi-N-ethyl-2-deoxystreptamine 
• 22389-04-4 1-deamino-2-deoxy-1-epi-hydroxystreptamine 
• 32385-11-8 sisomicin 
• 66065-86-9 N-[(1S,2R,3R,4S)-2-[(2S,3R)-3-Acetylamino-6-(acetylamino-methyl)-3,4-dihydro-2H-pyran-2-yloxy]-5-amino-4-((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-3-hydroxy-cyclohexyl]-acetamide 
• 66567-31-5 N-[(1S,2R,3S,4S)-2-[(2S,3R)-3-Acetylamino-6-(acetylamino-methyl)-3,4-dihydro-2H-pyran-2-yloxy]-4-((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylamino-tetrahydro-pyran-2-yloxy)-5-ethylamino-3-hydroxy-cyclohexyl]-acetamide 

Relevant articles and documents

Semisynthetic Aminoglycoside Antibacterials. Part 9. Synthesis of Novel 1- and 3-Substituted and 1- and 3-epi-Substituted Derivatives of Sisomicin and Gentamicin from the 1- and 3-Oxo-derivatives

The conversion of selectively protected gentamicin and sisomicin derivatives into the 1- and 3-oxo-compounds by reaction with 3,5-di-t-butyl-1,2-benzoquinone is described.By application of suitable reductive techniques these oxo-aminoglucosides have been converted into novel 1- and 3-epi-, 1- and 3-deamino-1- and -3-hydroxy-, 1- and 3-deamino-1- and -3-epi-hydroxy, and 1-deamino-derivatives.A study of the 13C n.m.r. parameters of the 1-epi- and 1-deamino-derivatives has led to the assignment of novel solution conformations for these new aminoglycosides.