223922-32-5

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 275386-60-2 4-(hydroxymethyl)-1-(trimethylsilylethynyl)benzene 
• 150969-54-3 ethyl 4-(trimethylsilylethynyl)benzoate 
• 10602-04-7 (4-ethynylphenyl)methanol 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 201815-81-8 (1R,2S)-2-((4-bromobenzyl)methylamino)-1-phenyl-1-propanol 
• 299-42-3 ephedrine 
• 242481-85-2 (1R,2S)-2-[Methyl-(4-trimethylsilanylethynyl-benzyl)-amino]-1-phenyl-propan-1-ol 
• 50-98-6 ephedrine hydrochloride 

Downstream Products

• 283597-75-1 (1R,2S)-2-({4-[3-(4-{[((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amino]-methyl}-phenylethynyl)-5-iodo-phenylethynyl]-benzyl}-methyl-amino)-1-phenyl-propan-1-ol 
• 399566-85-9 (1R,2S)-2-{[4-(3,5-Dibromo-phenylethynyl)-benzyl]-methyl-amino}-1-phenyl-propan-1-ol 
• 283597-81-9 (1R,2S)-2-({4-[3-(4-{[((1S,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amino]-methyl}-phenylethynyl)-5-trimethylsilanylethynyl-phenylethynyl]-benzyl}-methyl-amino)-1-phenyl-propan-1-ol 
• 283597-76-2 (1R,2S)-2-({4-[3-Ethynyl-5-(4-{[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amino]-methyl}-phenylethynyl)-phenylethynyl]-benzyl}-methyl-amino)-1-phenyl-propan-1-ol 

Relevant academic research and scientific papers

Synthesis of optically active polymers with chiral units attached to rigid backbones and their application for asymmetric catalysis

Optically active ephedrine-bearing poly(phenylene)s have been synthesized by using the Suzuki coupling polymerization. Their application as polymeric chiral catalysts for asymmetric addition of diethylzinc to aldehydes has been studied and good enantioselectivity was observed. The strategy to synthesize these optically active polymers is potentially useful in the design and synthesis of other polymeric chiral catalysts for asymmetric catalysis.

Synthesis of chiral dendrimers with a hydrocarbon backbone and application to the catalytic enantioselective addition of dialkylzincs to aldehydes

Chiral dendrimers with three or six β-amino alcohols on hyperbranched hydrocarbon chain-ends were synthesized. These macromolecules can act as chiral catalysts for the enantioselective addition of dialkylzincs to aldehydes. The corresponding secondary alc