224192-25-0

Basic information

• Product Name: (S)-(-)-methyl 2-[bis(tert-butoxycarbonyl)amino]-4-iodobutanoate
• CAS NO: 224192-25-0
• Molecular Weight: 443.279
• Mol File: 224192-25-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-(-)-methyl 2-[bis(tert-butoxycarbonyl)amino]-4-iodobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-methyl 2-[bis(tert-butoxycarbonyl)amino]-4-iodobutanoate(224192-25-0)
• EPA Substance Registry System: (S)-(-)-methyl 2-[bis(tert-butoxycarbonyl)amino]-4-iodobutanoate(224192-25-0)

Safety Data

• Hazardous Substances Data: 224192-25-0(Hazardous Substances Data)

Upstream product

• 219617-09-1 methyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}-4-oxobutanoate 
• 224192-24-9 methyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}-4-hydroxybutanoate 
• 748150-90-5 methyl (2S)-2-[bis(tert-butoxycarbonyl)amino]-4-methylsulfonyloxybutanoate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 130622-08-1 dimethyl N-tert-butoxycarbonyl-L-aspartate 
• 219617-08-0 dimethyl (2S)-2-{(tert-butoxy)-N-[(tert-butyl)oxycarbonyl]carbonylamino}butanedioate 

Downstream Products

• 21887-64-9 N₂-(tert-butoxycarbonyl)-L-ornithine 
• 108787-91-3 Boc-Arg(Boc)2OH 

Relevant articles and documents

Synthesis of Imidazole and Histidine-Derived Cross-Linkers as Analogues of GOLD and Desmosine

Amino acid derivatives with a central cationic heterocyclic core (e.g., imidazolium) are biologically relevant cross-linkers of proteins and advanced glycation end (AGE) products. Here, imidazolium-containing cross-linkers were synthesized from imidazole or histidine by N-alkylation employing aspartate- and glutamate-derived mesylates as key step. Biological investigations were carried out to probe the biocompatibility of these compounds.