22426-17-1

Basic information

• Product Name: 2-phenoxy-1,10-phenanthroline
• Synonyms: 2-phenoxy-1,10-phenanthroline
• CAS NO: 22426-17-1
• Molecular Weight: 272.306
• Mol File: 22426-17-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenoxy-1,10-phenanthroline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenoxy-1,10-phenanthroline(22426-17-1)
• EPA Substance Registry System: 2-phenoxy-1,10-phenanthroline(22426-17-1)

Safety Data

• Hazardous Substances Data: 22426-17-1(Hazardous Substances Data)

Upstream product

• 92695-50-6 1H-[1,10]phenanthrolin-2-one 
• 1891-19-6 1,10-phenanthroline N-oxide 
• 66-71-7 1,10-Phenanthroline 
• 22426-14-8 2--bromo-1,10--phenanthroline 
• 108-95-2 phenol 
• 7089-68-1 2-chloro-[1,10]phenanthroline 

Downstream Products

• 7089-68-1 2-chloro-[1,10]phenanthroline 

Relevant articles and documents

Chelation-assisted de-aryloxylative amination of 2-aryloxy quinolines: A new synthetic route to a key fragment of a bioactive PRMT5 inhibitor

A highly regioselective de-aryloxylative amination of O- or N-chelating group-functionalized 2-aryloxy quinolines has been accomplished by means of a copper catalyst. The chelating functional groups of the substrate play a crucial role in directing the C-

Copper-Catalyzed Regioselective C-H Amination of Phenol Derivatives with Assistance of Phenanthroline-Based Bidentate Auxiliary

A copper-catalyzed regioselective direct amination of phenol derivatives with diarylamines via phenanthroline-based bidentate auxiliary-directed C-H cleavage has been developed. This reaction proceeds smoothly with only a copper salt and air as a terminal oxidant to produce the corresponding o-aminophenols in good yields. Moreover, the directing group can be easily attached, detached, and recycled. Additionally, preliminary computational studies of the reaction with DFT have also been performed.