2244579-87-9Relevant academic research and scientific papers
Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief
Gado, Francesca,Di Cesare Mannelli, Lorenzo,Lucarini, Elena,Bertini, Simone,Cappelli, Elena,Digiacomo, Maria,Stevenson, Lesley A.,Macchia, Marco,Tuccinardi, Tiziano,Ghelardini, Carla,Pertwee, Roger G.,Manera, Clementina
, p. 276 - 287 (2019)
The direct activation of cannabinoid receptors (CBRs) results in several beneficial effects; therefore several CBRs ligands have been synthesized and tested in vitro and in vivo. However, none of them reached an advanced phase of clinical development due
