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8-(benzyloxy)-6,7-dimethoxy-3,4-dihydroisoquinoline is a complex organic compound belonging to the isoquinoline family. It features a dihydroisoquinoline core structure, which is a reduced form of isoquinoline, with two additional hydrogen atoms. The molecule is characterized by the presence of a benzyloxy group at the 8-position, which is a benzyl group (a phenylmethyl group) attached to an oxygen atom. Additionally, it has two methoxy groups at the 6 and 7 positions, which are methyl groups attached to oxygen atoms. 8-(benzyloxy)-6,7-dimethoxy-3,4-dihydroisoquinoline is known for its potential applications in medicinal chemistry, particularly in the synthesis of drugs targeting the central nervous system. Its structure provides a foundation for further chemical modifications, which can lead to the development of new therapeutic agents with improved pharmacological properties.

2245-88-7

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2245-88-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2245-88-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,4 and 5 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2245-88:
(6*2)+(5*2)+(4*4)+(3*5)+(2*8)+(1*8)=77
77 % 10 = 7
So 2245-88-7 is a valid CAS Registry Number.

2245-88-7Downstream Products

2245-88-7Relevant academic research and scientific papers

Synthetic approaches to pallimamine and analogues using direct imine acylation

Ronson, Thomas O.,Kitsiou, Christiana,Unsworth, William P.,Taylor, Richard J.K.

, p. 6099 - 6106 (2016)

The use of Direct Imine Acylation (DIA) methodology for the total synthesis of pallimamine is described, with three different synthetic routes examined. The construction of three advanced δ-lactam precursors, all utilising DIA, is described, along with attempts to progress these compounds further, using three distinct desymmetrisation strategies, two involving alcohol-aryl coupling, and a third involving an unusual diastereoselective lactonisation.

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