22458-53-3

Basic information

• Product Name: Benzoic acid, 4-(1,4-dihydro-4-oxo-2-thioxo-3(2H)-quinazolinyl)-
• CAS NO: 22458-53-3
• Molecular Formula: C15H10N2O3S
• Molecular Weight: 298.322
• Mol File: 22458-53-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(1,4-dihydro-4-oxo-2-thioxo-3(2H)-quinazolinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(1,4-dihydro-4-oxo-2-thioxo-3(2H)-quinazolinyl)-(22458-53-3)
• EPA Substance Registry System: Benzoic acid, 4-(1,4-dihydro-4-oxo-2-thioxo-3(2H)-quinazolinyl)-(22458-53-3)

Safety Data

• Hazardous Substances Data: 22458-53-3(Hazardous Substances Data)

Upstream product

• 16024-82-1 methyl 2-isothiocyanatobenzoate 
• 62-23-7 4-nitro-benzoic acid 
• 75-15-0 carbon disulfide 
• 150-13-0 4-amino-benzoic acid 
• 118-92-3 anthranilic acid 

Relevant articles and documents

Synthesis and reactions of some 3-aryl-2-thioxoquinazolin-4(3H)-ones

A series of 3-aryl-2-thioxoquinazolin-4(3H)-ones la-g are prepared in good yields from reactions of anthranilic acids, aromatic amines and carbon disulfide under basic conditions in one step. Reaction of aminophenyl derivatives la,b with D-glucose affords the corresponding N-glucosylamines 4a,b in very good yields. Diazotization of la,b followed by reactions with aromatic amines yield the corresponding azo dyes 6a-f in 40-56% yields. The fastness for 6 has been studied. Compounds 6a,b,f have been proved to biologically active.