224824-34-4

Basic information

• Product Name: 1H-Indole, 1-[(3,4-dicyanophenyl)sulfonyl]-
• CAS NO: 224824-34-4
• Molecular Formula: C16H9N3O2S
• Molecular Weight: 307.332
• Mol File: 224824-34-4.mol

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-[(3,4-dicyanophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-[(3,4-dicyanophenyl)sulfonyl]-(224824-34-4)
• EPA Substance Registry System: 1H-Indole, 1-[(3,4-dicyanophenyl)sulfonyl]-(224824-34-4)

Safety Data

• Hazardous Substances Data: 224824-34-4(Hazardous Substances Data)

Usage

Structure

A sulfonyl derivative of indole, a heterocyclic aromatic organic compound, with a (3,4-dicyanophenyl)sulfonyl group attached to the indole ring.

Reactivity

The sulfonyl group can participate in various chemical reactions, making it a versatile intermediate in organic synthesis.

Applications

Potential applications in pharmaceuticals and agrochemicals due to its unique structure and reactivity. It has been studied for its potential as a building block in the synthesis of various organic compounds and its biological activity.

Specific properties

The dicyanophenyl group attached to the sulfonyl group can impart specific properties and reactivity to the molecule, making it potentially useful in various chemical and biological applications.

Upstream product

• 170697-25-3 3,4-dicyanobenzenesulfonyl chloride 
• 583-53-9 2,3-dibromobenzene 
• 81903-80-2 3,4-dibromophenylsulfonic acid chloride 
• 544-92-3 copper(I) cyanide 
• 224824-31-1 1-(3,4-dibromophenylsulfonyl)indole 

Relevant articles and documents

AMPHIPHILIC TRISULFONATED PORPHYRAZINES FOR PHOTODYNAMIC APPLICATIONS IN MEDICINE

Disclosed herein are novel trisulfonated tribenzo-mononahptho-porphyrazines, processes for making them and their application as improved photosensitizing drugs for the treatment of various medical conditions by photodynamic therapy (PDT). These water-solu

Heterocyclic aromatic amide protecting groups for aryl and phthalocyaninesulfonic acids

Pyrroles, indole, imidazole, and a pyrazole were treated with 3,4-dibromobenzenesulfonyl chloride to form 3,4-dibromobenzenesulfonamides. The 1-(3,4-dibromophenylsulfonyl)pyrrole and 1-(3,4-dibromophenylsulfonyl)indole were stable to CuCN in DMF to produce 1-(3,4-dicyanophenylsulfonyl)pyrrole and 1-(3,4-dicyanophenylsulfonyl)indole, which upon treatment with ammonia in 2-N,N-dimethylaminoethanol gave the protected phthalocyanine-2,9,16,23-tetrasulfonamides. Base cleavage of these sulfonamides yielded the free acids. A mixed condensation of 4,5-diheptylphthalonitrile and 1-(3,4-dicyanophenylsulfonyl)pyrrole gave 9,10,16,17,23,24-hexakis(1-heptyl)-2-(1-pyrrolylsulfonyl)phthalocyanine. Cleavage of the latter yielded the lithium salt of the monosulfonic acid.