22492-49-5

Basic information

• Product Name: 1,2-Dibenzyl-1H-benzo[d]imidazole
• Synonyms: 1,2-Dibenzyl-1H-benzo[d]imidazole
• CAS NO: 22492-49-5
• Molecular Formula: C₂₁H₁₈N₂
• Molecular Weight: 298.38102
• Mol File: 22492-49-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Dibenzyl-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dibenzyl-1H-benzo[d]imidazole(22492-49-5)
• EPA Substance Registry System: 1,2-Dibenzyl-1H-benzo[d]imidazole(22492-49-5)

Safety Data

• Hazardous Substances Data: 22492-49-5(Hazardous Substances Data)

Usage

General Description

1,2-Dibenzyl-1H-benzo[d]imidazole is a chemical compound with the molecular formula C21H18N2. It is a benzimidazole derivative, which is a class of heterocyclic organic compounds. This particular compound is notable for its two benzyl groups attached to the imidazole ring, making it a dibenzyl derivative. It exists as a solid at room temperature and is often used in research and industrial applications as a building block for organic synthesis. Its structure and properties make it valuable for the creation of new pharmaceuticals, agrochemicals, and other specialized organic compounds. It is important to handle this chemical with care and adhere to safety protocols when working with it in a laboratory setting.

Upstream product

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Relevant articles and documents

Traceless synthesis of benzimidazoles on solid support

Traceless solid-phase syntheses of benzimidazoles and 5-(benzimidazol-2- yl)benzimidazoles on 2-(4-formyl-3-methoxyphenoxy)ethyl polystyrene are described. No auxiliary functional groups are left in the products after ultimate cleavage and cyclization.

Selective C-H trifluoromethylation of benzimidazoles through photoredox catalysis

The protocol presented here is a new strategy for visible light induced C-H trifluoromethylation at C4 of benzimidazoles using Togni's reagent in the presence of fac-Ir(ppy)3. Its advantages are its operational simplicity, mild reaction conditions, low catalyst loading and wide substrate scope in which electron-withdrawing, electron-donating groups and different protecting groups are tolerated.

Nickel catalyzed alkylation of N-aromatic heterocycles with Grignard reagents through direct C-H bond functionalization

A novel protocol for nickel-catalyzed direct sp2 C-H bond alkylation of N-aromatic heterocycles has been developed. This new reaction proceeded efficiently at room temperature using a Grignard reagent as the coupling partner. This approach prov