225122-40-7

Basic information

• Product Name: 4-(2-Chloroethylsulfanyl)-benzoic acid
• Synonyms: 4-(2-Chloroethylsulfanyl)-benzoic acid
• CAS NO: 225122-40-7
• Molecular Weight: 216.688
• Mol File: 225122-40-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(2-Chloroethylsulfanyl)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Chloroethylsulfanyl)-benzoic acid(225122-40-7)
• EPA Substance Registry System: 4-(2-Chloroethylsulfanyl)-benzoic acid(225122-40-7)

Safety Data

• Hazardous Substances Data: 225122-40-7(Hazardous Substances Data)

Upstream product

• 1074-36-8 4-mercaptobenzoic acid 
• 107-04-0 1-Bromo-2-chloroethane 
• 7184-99-8 4-((2-hydroxyethyl)thio)benzoic acid 

Downstream Products

• 225122-41-8 4-(2-chloroethylsulfanyl)-benzoyl-Leu-Gly(CN) 
• 17918-95-5 4-(2-Chloroethylsulfonyl)-benzoic acid 
• 257613-89-1 3-[1-methyl-4[1-methyl-4[1-methyl-4[4-(2-chloroethylsulfinyl)phenyl-1-carboxamido]pyrrole-2-carboxamido]pyrrole-2-carboxamido]pyrrole-2-carboxamido]propionamidine 
• 257300-86-0 C₃₀H₃₄ClN₉O₄S 

Relevant articles and documents

OXIDISED SULFURATED DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS

Compounds which are oxidised sulfurated distamycin derivatives of formula (I) wherein n is 2, 3 or 4; c is 1 or 2; A is a bond, a C1-C4 alkylene or C2-C4 alkenylene group; R1 and R2, which are the same or different, are selected from hydrogen, C1-C4 alkyl

Phenyl sulfur mustard derivatives of distamycin A

The design, synthesis, and cytotoxic activity of novel benzoyl and cinnamoyl sulfur mustard derivatives of distamycin A are described and structure-activity relationships are discussed. These sulfur mustards are more potent cytotoxics than corresponding nitrogen mustards in spite of the lower alkylating power, while their sulfoxide analogues are substantially inactive. Cinnamoyl sulfur mustard derivative (7) proved to be one of the most active distamycin-derived cytotoxics, about 1000 times more potent than melphalan. (C) 2000 Elsevier Science Ltd. All rights reserved.