225516-55-2

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 225516-43-8 3-[4-(2-hydroxy-ethyl)-piperazine-1-carbonyl]-6,7-dimethoxy-1-(3,4,5-trimethoxy-phenyl)-naphthalene-2-carboxylic acid methyl ester 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 70461-33-5 2-bromo-4,5-dimethoxybenzaldehyde dimethyl acetal 
• 1027968-88-2 (2-dimethoxymethyl-4,5-dimethoxy-phenyl)-(3,4,5-trimethoxy-phenyl)-methanol 
• 161359-54-2 6,7-dimethoxy-1-(3,4,5-trimethoxy-phenyl)-naphthalene-2,3-dicarboxylic acid dimethyl ester 
• 225516-13-2 6,7-dimethoxy-2-(methoxycarbonyl)-1-(3,4,5-trimethoxyphenyl)naphthalene-3-carboxylic acid 
• 103-76-4 1-(2-hydroxyethyl)piperazine 

Relevant academic research and scientific papers

1-arylnaphthalene lignan: A novel scaffold for type 5 phosphodiesterase inhibitor

1-Arylnaphthalene lignan, which had been reported as a PDE4 inhibitor by Iwasaki, was disclosed as a new structural class of PDE5 inhibitors. The structural requirements for potent and specific PDE5 inhibition were revealed in a 1-arylnaphthalene lignan s