225525-50-8 Usage
Uses
Used in Pharmaceutical Industry:
2-N-BOC-AMINO-4-BENZOTHIAZOLE-6-CARBOXYLIC ACID is used as a pharmaceutical intermediate for the development of drugs with potential anticancer, antimicrobial, and anti-inflammatory properties. The benzothiazole core and carboxylic acid functionality contribute to its diverse biological activities and synthetic utility.
Used in Organic Synthesis:
2-N-BOC-AMINO-4-BENZOTHIAZOLE-6-CARBOXYLIC ACID is used as a building block in organic synthesis for the preparation of various organic molecules. The presence of the carboxylic acid group allows for further functionalization and derivatization, enabling the synthesis of complex organic compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 225525-50-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,5,5,2 and 5 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 225525-50:
(8*2)+(7*2)+(6*5)+(5*5)+(4*2)+(3*5)+(2*5)+(1*0)=118
118 % 10 = 8
So 225525-50-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2O4S/c1-13(2,3)19-12(18)15-11-14-8-5-4-7(10(16)17)6-9(8)20-11/h4-6H,1-3H3,(H,16,17)(H,14,15,18)
225525-50-8Relevant academic research and scientific papers
Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents
Cai, Jin,Sun, Min,Wu, Xiaoqing,Chen, Junqing,Wang, Peng,Zong, Xi,Ji, Min
, p. 702 - 712 (2013/07/27)
Three series of novel 4-benzothiazole amino quinazolines Dasatinib derivatives have been designed and synthesized. The entire target compounds were investigated for their in vitro cytotoxic activity by the MTT-based assay against 6 human cancer cell lines
Molecular design, synthesis, and structure-activity relationships leading to the potent and selective p56lck inhibitor BMS-243117
Das, Jagabandhu,Lin, James,Moquin, Robert V.,Shen, Zhongqi,Spergel, Steven H.,Wityak, John,Doweyko, Arthur M.,DeFex, Henry F.,Fang, Qiong,Pang, Suhong,Pitt, Sidney,Shen, Ding Ren,Schieven, Gary L.,Barrish, Joel C.
, p. 2145 - 2149 (2007/10/03)
A series of structurally novel benzothiazole based small molecule inhibitors of p56lck were prepared to elucidate their structure-activity relationships (SARs), selectivity and cell activity in the T-cell proliferation assay. BMS-243117 (compound 2) is identified as a potent, and selective Lck inhibitor with good cellular activity (IC50=1.1 μM) against T-cell proliferation.
