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(5-Chloro-3-pyridinyl)methanol is an organic compound with the molecular formula C?H?ClNO and a molecular weight of approximately 141.58 g/mol. It is a colorless to pale yellow liquid at room temperature and is characterized by its distinct chemical structure, which features a chlorinated pyridine ring and a hydroxymethyl group. (5-Chloro-3-pyridinyl)methanol is known for its reactivity and is commonly used as a synthetic intermediate in the pharmaceutical and chemical industries.

22620-34-4

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22620-34-4 Usage

Uses

Used in Pharmaceutical Industry:
(5-Chloro-3-pyridinyl)methanol is used as a synthetic intermediate for the preparation of piperidines or piperidones substituted with urea and heteroaryl as FPR2 modulators. These modulators play a crucial role in the development of drugs targeting the formyl peptide receptor 2 (FPR2), which is involved in various physiological processes, including inflammation, pain, and immune response regulation. By modulating FPR2, these compounds have the potential to treat a range of conditions, such as chronic pain, inflammatory diseases, and certain types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 22620-34-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,6,2 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 22620-34:
(7*2)+(6*2)+(5*6)+(4*2)+(3*0)+(2*3)+(1*4)=74
74 % 10 = 4
So 22620-34-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClNO/c7-6-1-5(4-9)2-8-3-6/h1-3,9H,4H2

22620-34-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-Chloro-3-pyridinyl)methanol

1.2 Other means of identification

Product number -
Other names (5-chloropyridin-3-yl)methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22620-34-4 SDS

22620-34-4Relevant academic research and scientific papers

SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

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Paragraph 0321, (2015/07/02)

Provided herein are diaminopyrimidyl Compounds having the following structures: wherein X, L, R1, and R2 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidyl Compound, and methods for treating or preventing PKC-theta-mediated disorders, or a condition treatable or preventable by inhibition of a kinase, for example, PKC-theta.

FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES IV

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Page/Page column 53, (2015/07/07)

The invention relates to pyrrole carboxamides bearing a fluoromethyl- moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

THERAPEUTIC SUBSTITUTED CYCLOPENTANES FOR REDUCING INTRAOCULAR PRESSURE

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Page/Page column 28, (2009/03/07)

Disclosed herein are compounds having formula (I) wherein a dashed line represents the presence or absence of a bond; Y is an organic acid functional group, or an amide or ester thereof; or Y is hydroxymethyl or an ether thereof; or Y is a tetrazolyl func

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