51269-81-9

Basic information

• Product Name: 5-Chloropyridine-3-carboxylic acid methyl ester
• Synonyms: 5-Chloropyridine-3-carboxylic acid methyl ester;Methyl 5-chloronicotinate;5-Chlor-nicotinsaeure-Methylester;Methyl 5-chloropyridine-3-carboxylate;Methyl 3-chloropyridine-5-carboxylate;5-chloro-3-Pyridinecarboxylic acid methyl ester;3-Pyridinecarboxylic acid, 5-chloro-, methyl ester
• CAS NO: 51269-81-9
• Molecular Formula: C7H6ClNO2
• Molecular Weight: 171.58104
• Product Categories: Heterocycle-Pyridine series
• Mol File: 51269-81-9.mol

Chemical Properties

• Melting Point: 88-90 °C
• Boiling Point: 230.4 °C at 760 mmHg
• Flash Point: 93.1 °C
• Appearance: /
• Density: 1.294 g/cm³
• Vapor Pressure: 0.066mmHg at 25°C
• Refractive Index: 1.531
• Storage Temp.: 2-8°C
• PKA: 0.91±0.20(Predicted)
• CAS DataBase Reference: 5-Chloropyridine-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloropyridine-3-carboxylic acid methyl ester(51269-81-9)
• EPA Substance Registry System: 5-Chloropyridine-3-carboxylic acid methyl ester(51269-81-9)

Safety Data

• Hazardous Substances Data: 51269-81-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloropyridine-3-carboxylic acid methyl ester is used as an intermediate for the production of various drugs, contributing to the development of new medications and improving existing ones.
Used in Agrochemical Industry:
5-Chloropyridine-3-carboxylic acid methyl ester is used as a building block in the synthesis of agrochemicals, aiding in the creation of effective pesticides and other agricultural products.
Used in Organic Chemistry:
5-Chloropyridine-3-carboxylic acid methyl ester serves as a versatile building block in organic chemistry, enabling the synthesis of a wide range of organic compounds for various applications.

InChI:InChI=1/C7H6ClNO2/c1-11-7(10)5-2-6(8)4-9-3-5/h2-4H,1H3

Upstream product

• 67-56-1 methanol 
• 22620-27-5 5-chloronicotinic acid 
• 56055-54-0 methyl 2,3-dichloro-pyridine-5-carboxylate 
• 201230-82-2 carbon monoxide 

Downstream Products

• 22620-34-4 (5-chloro-pyridin-3-yl)-methanol 
• 1423715-17-6 (E)-5-chloro-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)nicotinohydrazide 
• 117830-18-9 5-chloropyridine-3-carbohydrazide 

Relevant articles and documents

TRIAZOLE AGONISTS OF THE APJ RECEPTOR

Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures where the definitions of the variables are provided herein.

BENZENE SULFONAMIDES AS CCR9 INHIBITORS

The present invention relates to compounds useful as CCR9 modulators, to compositions containing them, to methods of making them, and to methods of using them. In particular, the present invention relates to compounds capable of modulating the function of the CCR9 receptor by acting as partial agonists, antagonists or inverse agonists. Such compounds may be useful to treat, prevent or ameliorate a disease or condition associated with CCR9 activation, including inflammatory and immune disorder diseases or conditions such as inflammatory bowel diseases (IBD).

High-throughput virtual screening identifies novel N ′-(1- phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors

Lysine specific demethylase 1 (LSD1) plays an important role in regulating histone lysine methylation at residues K4 and K9 on histone H3 and is an attractive therapeutic target in multiple malignancies. Here we report a structure-based virtual screen of

SUBSTITUTED (E)-N'-(1-PHENYLETHYLIDENE) BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIITORS

In one aspect, the invention relates to substituted (E)-N'-(1- phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods fo

THERAPEUTIC SUBSTITUTED CYCLOPENTANES FOR REDUCING INTRAOCULAR PRESSURE

Disclosed herein are compounds having formula (I) wherein a dashed line represents the presence or absence of a bond; Y is an organic acid functional group, or an amide or ester thereof; or Y is hydroxymethyl or an ether thereof; or Y is a tetrazolyl func

Selective alkoxycarbonylation of 2,3-dichloropyridines

2,3-Dichloropyridines undergo a motto- or a dicarbonylation in the presence of carbon monoxide, an alcohol and a palladium catalyst, affording selectively either alkyl 3-chloropicolinates, or dialkyl pyridine-2,3- dicarboxylates in good yields, depending on the reaction conditions.