226387-80-0

Basic information

• Product Name: Benzenemethanol, 4-(1-methylethyl)-a-2-propynyl-
• CAS NO: 226387-80-0
• Molecular Formula: C13H16O
• Molecular Weight: 188.269
• Mol File: 226387-80-0.mol

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-(1-methylethyl)-a-2-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-(1-methylethyl)-a-2-propynyl-(226387-80-0)
• EPA Substance Registry System: Benzenemethanol, 4-(1-methylethyl)-a-2-propynyl-(226387-80-0)

Safety Data

• Hazardous Substances Data: 226387-80-0(Hazardous Substances Data)

Upstream product

• 18295-60-8 allenylmagnesium bromide 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 106-96-7 propargyl bromide 

Downstream Products

• 194095-62-0 (5E)-6-chloro-1-(p-isopropylphenyl)hex-5-en-3-yn-1-ol 
• 1083055-80-4 1-(4'-isopropylphenyl)penta-3,4-dien-1-ol 
• 226388-38-1 (1E,3E,5E,9E,11E,13E)-1-(p-isopropylphenyl)-14-phenyltetradeca-1,3,5,9,11,13-hexaen-7-yne 
• 226388-30-3 (3E,5E,7E)-8-(p-isopropylphenyl)-1-trimethylsilylocta-3,5,7-trien-1-yne 
• 194095-66-4 (3E,5E)-6-chloro-1-(p-isopropylphenyl)hexa-3,5-diene 
• 194095-71-1 (1E,3E,5E)-1-chloro-6-(p-isopropylphenyl)-1,3,5-hexatriene 

Relevant articles and documents

A facile lipase-catalyzed KR approach toward enantiomerically enriched homopropargyl alcohols

Compounds possessing propargylic (prop-2-ynylic) system are very important building blocks for organic chemistry. Among them, preparation of enantiomeric homopropargyl alcohols (but-3-yn-1-ols) constitutes a key-challenge for asymmetric synthesis and thus

A bicyclization reaction with two molecular allenyl ketones and isocyanides: Synthesis of a lactone-containing azaspirocycle derivative

A novel bicyclization reaction of two molecular allenyl ketones and isocyanides has been disclosed. This strategy allows for the construction of structurally complex spirocyclic lactam-lactone systems in an efficient manner. This protocol also demonstrate

Efficient synthesis of 3-chloromethyl-2(5H)-furanones and 3-chloromethyl- 5,6-dihydropyran-2-ones via the PdCl2-catalyzed chlorocyclocarbonylation of 2,3- or 3,4-allenols

(Chemical Equation Presented) A mild and efficient methodology involving PdCl2-catalyzed chlorocyclocarbonylation of 2,3- or 3,4-allenols with CuCl2 for the synthesis of 3-chloromethyl-2(5H)-furanones and 3-chloromethyl-5,6-dihydropyran-2-ones was developed. This reaction proceeded in a highly regioselective manner, i.e., the chlorine atom was introduced to the terminal position of the allene moiety while the lactone linkage was formed between the center carbon atom of the allene moiety and the hydroxyl oxygen, which was established by the X-ray single crystal diffraction study of γ-lactone 3p. The highly optically active 3-chloromethyl-2(5H)-furanones could be easily prepared from the readily available optically active 2,3-allenols. A mechanism for this reaction was proposed.