226396-62-9

Basic information

• Product Name: 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate
• Synonyms: 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate
• CAS NO: 226396-62-9
• Molecular Formula: C₁₉H₂₆FNO₄S
• Molecular Weight: 0
• Mol File: 226396-62-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate(226396-62-9)
• EPA Substance Registry System: 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate(226396-62-9)

Safety Data

• Hazardous Substances Data: 226396-62-9(Hazardous Substances Data)

Usage

Chemical class

piperidine class of drugs

Common use

scientific research, potential therapeutic effects

Known for

analgesic or pain reliever properties

Molecular structure

piperidine ring and carboxylate groups

Pharmaceutical properties

specific properties due to molecular structure

Potency

highly potent

Receptor affinity

high affinity for certain body receptors

Drug development

promising candidate for further development

Studies needed

further studies required to understand pharmacological effects and applications

Handling

should be regulated and handled by trained professionals in appropriate laboratory settings

Upstream product

• 405-31-2 bis(4-fluorophenyl)disulfide 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 371-42-6 4-Fluorothiophenol 

Downstream Products

• 226388-60-9 SC 276 
• 226396-67-4 4-(4-phenylsulfanyl-benzenesulfonyl)-1-prop-2-ynyl-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 226397-43-9 1-cyclopropyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 226397-53-1 1-(2-methoxy-ethyl)-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 226401-16-7 1-methanesulfonyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 869063-76-3 1-ethyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 226397-45-1 1-methyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid (tetrahydro-pyran-2-yloxy)-amide 
• 226397-38-2 1-tert-butyl 4-ethyl 4-{[4-(phenylthio)phenyl]sulfonyl}piperidine-1,4-dicarboxylate 
• 226396-65-2 4-(4-phenylsulfanyl-benzenesulfonyl)-1-prop-2-ynyl-piperidine-4-carboxylic acid ethyl ester 
• 226397-54-2 4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-1,4-dicarboxylic acid mono-tert-butyl ester 
• 226397-42-8 1-cyclopropyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester 
• 226396-66-3 4-(4-phenylsulfanyl-benzenesulfonyl)-1-prop-2-ynyl-piperidine-4-carboxylic acid 
• 226397-21-3 1-allyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester 
• 226401-14-5 1-methanesulfonyl-4-(4-phenylsulfanyl-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester 

Relevant articles and documents

CARBORANE HYDROXAMIC ACID MATRIX METALLOPROTEINASE INHIBITORS AND AGENTS FOR BORON NEUTRON CAPTURE THERAPY

Disclosed herein are novel carborane hydroxamic acid matrix metalloproteinase ("MMP") inhibitors and agents bearing borane-containing moieties and methods for their use in treating or preventing a disease, such as cancer and rheumatoid arthritis. In parti

Synthesis and structure-activity relationships of β- and α-piperidine sulfone hydroxamic acid matrix metalloproteinase inhibitors with oral antitumor efficacy

α-Piperidine-β-sulfone hydroxamate derivatives were explored that are potent for matrix metalloproteinases (MMP)-2, -9, and -13 and are sparing of MMP-1. The investigation of the β-sulfones subsequently led to the discovery of hitherto unknown α-sulfone h