1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate

Base Information

Chemical Name:1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate
CAS No.:226396-62-9
Molecular Formula:C19H26 F N O4 S
Molecular Weight:383.484
Hs Code.:
Mol file:226396-62-9.mol

Synonyms:1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate

Suppliers and Price of 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-TERT-BUTYL-4-ETHYL 4-(4-FLUOROPHENYLTHIO)PIPERIDINE-1,4-DICARBOXYLATE 95.00%
5MG
$ 503.91

Total 2 raw suppliers

Chemical Property of 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate

Chemical Property:

PSA：81.14000
LogP:4.18850

Purity/Quality:

99% ^*data from raw suppliers

1-TERT-BUTYL-4-ETHYL 4-(4-FLUOROPHENYLTHIO)PIPERIDINE-1,4-DICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate

There total 2 articles about 1-tert-Butyl-4-ethyl 4-(4-fluorophenylthio)piperidine-1,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 405-31-2
bis(4-fluorophenyl)disulfide

: 142851-03-4
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

: 226396-62-9
1-tert-butyl 4-ethyl 4-[(4-fluorophenyl)thio]piperidine-1,4-dicarboxylate

Guidance literature:: 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate; With lithium diisopropyl amide; In tetrahydrofuran; ethylbenzene; at -78 - 0 ℃; for 0.366667h;

bis(4-fluorophenyl)disulfide; In tetrahydrofuran; ethylbenzene; at -40 - 20 ℃;

Reference yield:

: 371-42-6
4-Fluorothiophenol

: 226396-62-9
1-tert-butyl 4-ethyl 4-[(4-fluorophenyl)thio]piperidine-1,4-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: dimethyl sulfoxide / 8 h / 65 °C

2.1: lithium diisopropyl amide / tetrahydrofuran; ethylbenzene / 0.37 h / -78 - 0 °C

2.2: -40 - 20 °C

With lithium diisopropyl amide; In tetrahydrofuran; ethylbenzene; dimethyl sulfoxide;