226397-23-5

Basic information

• Product Name: 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester
• Synonyms: 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester
• CAS NO: 226397-23-5
• Molecular Weight: 443.564
• Mol File: 226397-23-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester(226397-23-5)
• EPA Substance Registry System: 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester(226397-23-5)

Safety Data

• Hazardous Substances Data: 226397-23-5(Hazardous Substances Data)

Upstream product

• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 113113-66-9 1,2-bis(4-phenoxyphenyl)disulfane 
• 226396-40-3 1-tert-butyl 4-ethyl 4-[(4-phenoxyphenyl)thio]piperidine-1,4-dicarboxylate 
• 226396-42-5 1-tert-butyl 4-ethyl 4-[(4-phenoxyphenyl)sulfonyl]piperidine-1,4-dicarboxylate 
• 7051-34-5 cyclopropylcarbinyl bromide 

Downstream Products

• 226401-75-8 1-cyclopropylmethyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid 

Relevant articles and documents

Synthesis and structure-activity relationships of β- and α-piperidine sulfone hydroxamic acid matrix metalloproteinase inhibitors with oral antitumor efficacy

α-Piperidine-β-sulfone hydroxamate derivatives were explored that are potent for matrix metalloproteinases (MMP)-2, -9, and -13 and are sparing of MMP-1. The investigation of the β-sulfones subsequently led to the discovery of hitherto unknown α-sulfone h