22655-93-2Relevant academic research and scientific papers
The Use of Methoxy(phenyldimethylsilyl)methyl-lithium as a Formyl Anion Equivalent
Ager, David J.,Gano, James E.,Parekh, Shyamal I.
, p. 1256 - 1258 (1989)
Methoxy(phenyldimethylsilyl)methyl-lithium provides a new formyl anion equivalent which affords α-hydroxyaldehydes via an oxidative desilylation procedure.
Electroorganic Synthesis, 57. Synthesis of Advanced Prostaglandin Precursors by Kolbe Electrolysis, II. - Preparation of Coacids and Anodic Initiated Tandem Radical-Addition/Radical-Coupling Reaction with (1'R,4'S,3R/S)-3-(cis-4-Acetoxycyclopent-2-enyloxy)-3-ethoxypropionic Acid
Weiguny, Jens,Schaefer, Hans J.
, p. 235 - 242 (2007/10/02)
The α-silyl-substituted carboxylic acids 4 and 10 were prepared and with other coacids subjected to a mixed Kolbe electrolysis with β-cyclopentenyloxypropanoate 1.The stereochemical course of this cyclization reaction was determined on the basis of the 4-methyl-substituted product 23 by 1H-NMR-NOE spectroscopy.Conversion of the bicyclic reaction products 21b-d to advanced prostaglandin precursors such as lactone 30 was achieved in few steps. - Key Words: Kolbe elecrolysis / Radical cyclization / Si-C bond oxidation / Prostaglandins
N-ETHYLENEDIAMINES
Hu, Chunye,He, Ji-Gang,O'Brien, D. H.,Irgolic, K. J.
, p. 31 - 38 (2007/10/02)
A series of N-organosilylalkyl-substituted ethylenediamines, R3Si(CH2)nNHCH2CH2NH2 (R = CH3, C6H5 or 4-CH3C6H4; n = 1 or 3), were prepared by the reaction of haloalkylsilanes with ethylenediamine.The cleavage of a methyl group from silicon by concentrated sulfuric acid was used for the preparation of 1,3-bis-1,1,3,3-tetramethyldisiloxane.The proton and carbon-13 NMR spectra of these compounds are reported.
