22668-63-9Relevant academic research and scientific papers
METHYLPHOSPHONIC DICHLORIDE AS REAGENT FOR THE DETERMINATION OF THE ENANTIOMERIC EXCESS OF CHIRAL THIOLS. SCOPE AND LIMITATIONS
Strijtveen, Bert,Feringa, Ben L.,Kellogg, Richard M.
, p. 123 - 130 (2007/10/02)
Methylphosphonic dichloride, CH3P(=O)Cl2, reacts cleanly and quantitatively with thiols to form dialkylthiophosphonates, CH3P(=O)(SR)2.From the ratio of the integrations of the 31P absorptions in the NMR spectra, the enantiomeric excesses of the thiols ca
ALKYLPHOSPHONIC DICHLORIDES, NEW REAGENTS FOR THE ENANTIOMERIC EXCESS DETERMINATION OF CHIRAL ALCOHOLS AND THIOLS BY 31P NMR
Feringa, Ben L.,Smaardijk, Ab A.,Wynberg, Hans,Strijtveen, Bert,Kellog, Richard M.
, p. 997 - 1000 (2007/10/02)
The enantiomeric excess of chiral alcohols and thiols (1) is obtained by 31P NMR measurements of the ratios of diastereoisomeric (thio)phosphonates from 1 and methylphosphonic dichloride.
