226992-13-8

Basic information

• Product Name: 4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine
• Synonyms: 4-NITRO-N-2-(4-NITROPHENOXY)ETHYLBENZENEETHANAMINE;[2-(4-nitrophenoxy)ethyl][2-(4-nitrophenyl)ethyl]aMine
• CAS NO: 226992-13-8
• Molecular Formula: C₁₆H₁₇N₃O₅
• Molecular Weight: 331.32
• Mol File: 226992-13-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 58-60 °C
• Boiling Point: 520.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.293±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 7.95±0.19(Predicted)
• CAS DataBase Reference: 4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine(226992-13-8)
• EPA Substance Registry System: 4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine(226992-13-8)

Safety Data

• Hazardous Substances Data: 226992-13-8(Hazardous Substances Data)

Usage

General Description

4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine is a chemical compound with the molecular formula C16H15N3O6. It is a nitro derivative of ethylnoradrenaline and contains a nitro group, an amine group, and a benzene ring. 4-Nitro-N-[2-(4-nitrophenoxy)ethyl]benzeneethanamine is often used in organic synthesis and pharmaceutical research as a building block for the production of various drugs and other organic compounds. It has the potential to exhibit biological activity and may be used in the development of new pharmaceuticals. However, it is important to handle this chemical with caution, as it is potentially hazardous and may pose health risks if not used properly.

Upstream product

• 24954-67-4 2-(p-nitrophenyl)ethylamine 
• 13288-06-7 1-(2-bromoethoxy)-4-nitrobenzene 
• 64-04-0 phenethylamine 
• 6270-07-1 N-<2-(4-nitrophenyl)ethyl>acetamide 
• 877-95-2 methyl-N-(benzyl-methyl)-formamide 
• 100-02-7 4-nitro-phenol 
• 69447-84-3 p-nitrophenethylamine hydrobromide 

Downstream Products

• 248599-61-3 N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 
• 176447-94-2 [Cy₃B]-N-Demethyldofetilide 
• 446877-49-2 N-allyl-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 
• 226992-23-0 N-(p-chlorobenzyl)-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 
• 446877-50-5 N-benzoyl-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 
• 226992-14-9 N-benzyl-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 
• 226992-21-8 N-acetyl-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine 

Relevant articles and documents

7-(lH-PYRAZOL-4-YL)-1,6-NAPHTHYRIDINE COMPOUNDS AS SYK INHIBITORS

The present invention relates to a compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast and/or basophil cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, chronic spontaneous urticaria and autoimmune conditions.

PYRIMIDINECARBOXAMIDE DERIVATIVES AS INHIBITORS OF SYK KINASE

The compound of formula (I) or a salt, preferably a pharmaceutically acceptable salt, thereof; is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate mast cell activation, for ins