227029-24-5Relevant articles and documents
Inhibitors of prenyl-protein transferase
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, (2008/06/13)
The present invention is directed to conformationally constrained compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
1,3,8,-triaza spiro (4,5)decan-4-on derivatives
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, (2008/06/13)
The present invention relates to compounds of formula I and pharmaceutically acceptable acid addition salts thereof.