227100-23-4

Basic information

• Product Name: 4-Piperidinol, 1-(triphenylmethyl)-
• Synonyms: 4-hydroxy-N-tritylpiperidine;1-(triphenylmethyl)piperidin-4-ol
• CAS NO: 227100-23-4
• Molecular Formula: C24H25NO
• Molecular Weight: 343.469
• Mol File: 227100-23-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 479.0±40.0 °C(Predicted)
• Density: 1.145±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Piperidinol, 1-(triphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinol, 1-(triphenylmethyl)-(227100-23-4)
• EPA Substance Registry System: 4-Piperidinol, 1-(triphenylmethyl)-(227100-23-4)

Safety Data

• Hazardous Substances Data: 227100-23-4(Hazardous Substances Data)

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 76-83-5 trityl chloride 

Downstream Products

• 1402930-49-7 C₄₁H₃₉NO₃ 
• 1402930-47-5 C₄₀H₃₇NO₃ 
• 1402930-45-3 (3-methyl-4-{[1-(triphenylmethyl)piperidin-4-yl]oxy}-1-benzofuran-2-yl)methanol 
• 1402930-16-8 4-({2-[(benzyloxy)methyl]-3-methyl-1-benzofuran-4-yl}oxy)piperidine 
• 1402930-14-6 4-{[3-methyl-2-(phenoxymethyl)-1-benzofuran-4-yl]oxy}piperidine 
• 1402930-43-1 ethyl 3-methyl-4-{[1-(triphenylmethyl)-piperidin-4-yl]oxy}-1-benzofuran-2-carboxylate 
• 112257-60-0 1-triphenylmethyl-4-piperidone 
• 124256-77-5 N-trityl-3-piperidinyl methanesulfonate 
• 124256-45-7 7-(N-trityl-4-piperidinyl)thio-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 

Relevant articles and documents

NOVEL COMPOUNDS AND THEIR USE IN THERAPY

The invention provides compounds which inhibit N-myristoyltransferase and are selective for protozoal N-myristoyltransferase and, consequently suitable to treat microbial infections, including viral and fungal infections, and protozoan infections such as malaria, leishmaniasis and sleeping sickness.

Urethanes derived from azacycloalkanes, the thio and dithio analogues thereof and their use as cholesterol biosynthesis inhibitors

The present invention relates to urethanes derived from azacycloalkanes and the thio and dithio analogues thereof of general formula wherein m, n, A, X, Y, E and R1to R8are defined as in claim 1, the enantiomers, diastereomers and the salts thereof, particularly the physiologically acceptable acid addition salts thereof which have valuable properties, particularly an inhibitory effect on cholesterol biosynthesis, pharmaceutical compositions containing these compounds, their use and processes for preparing them.