22718-48-5

Usage

Uses

Used in Pharmaceutical Industry:
1-methylhydrazinecarboxamide is used as a pharmaceutical intermediate for the synthesis of various drugs due to its versatile chemical properties and potential therapeutic effects.
Used in Cardiovascular Applications:
1-methylhydrazinecarboxamide is used as a vasodilator and diuretic agent for the treatment of cardiovascular diseases and hypertension, helping to improve blood flow and reduce blood pressure.
Used in Antihypertensive Applications:
1-methylhydrazinecarboxamide is used as an antihypertensive agent, leveraging its vasodilator properties to manage high blood pressure effectively.
Used in Antitumor Applications:
1-methylhydrazinecarboxamide is used as a potential antitumor agent, with ongoing research exploring its effects on inhibiting tumor growth and progression.
Used in Antiparasitic Applications:
1-methylhydrazinecarboxamide is used as a potential antiparasitic agent, with studies investigating its ability to combat parasitic infections.

Upstream product

• 684-93-5 1-methyl-1-nitrosourea 
• 590-28-3 potassium cyanate 
• 302-15-8 methylhydrazine sulfuric acid 
• 60-34-4 methylhydrazine 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 1118-02-1 trimethylsilyl isocyanate 
• 917-61-3 sodium isocyanate 

Downstream Products

• 6281-25-0 5-Nitro-furaldehyd-(2)-(1-methyl-semicarbazon) 
• 4114-33-4 methyl-hydrazine-N,N'-dicarboxylic acid diamide 
• 54034-38-7 1-methyl-3-phenyl-Δ³-1,2,4-triazolin-5-one 
• 21009-76-7 benzaldehyde-(2-methyl semicarbazone) 
• 18510-97-9 2-methyl-5,6-diphenyl-1,2,4-triazin-3(2H)-one 
• 3190-41-8 2-Methylsemicarbazid-dicarbimidsaeure-(1,1)-bis-p-tolylester 
• 16813-40-4 1,4-Dimethylbiurea 
• 3190-42-9 2-Methyl-semicarbazid-dicarbimidsaeure-(1.1)-bis-(3-chlorphenylester) 
• 3190-40-7 2-Methyl-semicarbazid-di-carbimidsaeure-(1,1)-bis-(2,4-dimethyl-phenylester) 
• 343314-82-9 5-(difluoromethyl)-1,2-dihydro-2-methyl-3H-1,2,4-(triazol)-3-one 
• 6623-86-5 2-methyl-3,5-dioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 1380401-00-2 N-(benzyloxycarbonyl)glycyl-azaalanine-amide 

Relevant academic research and scientific papers

Methylsemicarbazide as a Ligand in Late 3d Transition Metal Complexes

Most ignition and initiation systems nowadays still contain poisonous chemicals such as lead styphnate and lead azide but also chromates and other compounds of high concern. Therefore, methylsemicarbazide (1, MSC), which can be prepared in a one-step reaction and in an extraordinary high yield of 95 %, has been evaluated as ligand in energetic coordination compounds. For the first time 25 new transition metal complexes (Mn2+, Ni2+, Co2+, Cu2+, and Zn2+) using methylsemicarbazide (1) as the ligand were prepared and comprehensively analyzed by, for example, XRD, IR, EA, UV/Vis and DSC/DTA/TGA. Many show a strong energetic character, which can be tuned by using different anions such as Cl?, SO42?, NO3?, ClO4?, picrate or styphnate. Selected compounds were additionally evaluated as lead-free primary explosives in initiation tests (nitropenta filled detonators) and in laser ignition systems. Especially compound 7 showed very promising results during these tests and could be a potential candidate for future applications.

N2-Alkylation of semicarbazones. A general and efficient protocol for the synthesis of 2-alkylsemicarbazides from semicarbazide

Synthesis of 2-alkylsemicarbazones based on selective N2-alkylation of semicarbazones has been described. The synthesis involves deprotonation of semicarbazones with sodium hydride in MeCN followed by treatment with alkylating reagents. The developed alkylation method was applied to the preparation of hardly available 2-alkylsemicarbazides and their hydrochlorides from semicarbazide hydrochloride. This general and efficient protocol is based on preparation of acetone semicarbazone, its alkylation, and hydrolysis under mild conditions.

INHIBITORS OF MALT1 PROTEASE

The present invention relates to compounds which are inhibitors of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALTl) and to their use in therapy, in particular in the treatment or prevention of a disease or disorder which is treatable by an inhibitor of a paracaspase. The present invention also relates to pharmaceutical compositions containing such compounds.

6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES

Disclosed are compounds exhibiting sufficient herbicidal activity at low application dosage when they are applied to soils and foliage, and an agrochemical composition using the same, in particular herbicides. The compounds are triazine derivatives repres

Induction of chirality: Experimental evidence of atropisomerism in azapeptides

Methylation of the peptide bond in model azadipeptides leads to the E configuration and hence to atropisomerism due to a restricted rotation around the N-N axis. This journal is

HETEROCYCLIC HYDRAZONE COMPOUNDS AND THEIR USES TO TREAT CANCER AND INFLAMMATION

The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).

Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof

A triazolone compound of the formula [I]: wherein; R1 represents optionally substituted phenyl or the like, T represents m-phenylene optionally substituted by methyl or the like; and a fungicidal composition containing it as an active ingredient.