22743-00-6

Basic information

• Product Name: 1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester
• Synonyms: 1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester;1,2,3,4-Tetrahydro-4-oxo-2-naphthoic acid ethyl ester;Ethyl 4-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate
• CAS NO: 22743-00-6
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.2485
• Mol File: 22743-00-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 332.7°Cat760mmHg
• Flash Point: 146.1°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 0.000143mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester(22743-00-6)
• EPA Substance Registry System: 1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester(22743-00-6)

Safety Data

• Hazardous Substances Data: 22743-00-6(Hazardous Substances Data)

Usage

General Description

1,2,3,4-Tetrahydro-4-oxo-2-naphthalenecarboxylic acid ethyl ester, also known as tetraline carboxylic acid ethyl ester, is a chemical compound with the molecular formula C13H14O3. It is a synthetic organic compound that is commonly used in the production of pharmaceuticals and agricultural products. This chemical is derived from naphthalene and contains a carbonyl group, making it a key component in the synthesis of various drugs and pesticides. It is often used as a building block for the construction of more complex molecules, and its versatility makes it a valuable tool in the field of organic chemistry. However, it is important to handle this chemical with care, as it can be hazardous if not properly managed.

InChI:InChI=1/C13H14O3/c1-2-16-13(15)10-7-9-5-3-4-6-11(9)12(14)8-10/h3-6,10H,2,7-8H2,1H3

Upstream product

• 75-65-0 tert-butyl alcohol 
• 67-56-1 methanol 

Downstream Products

• 1592-38-7 2-Naphthalenemethanol 

Relevant articles and documents

Photoinduced electron-transfer reaction of α-bromomethyl-substituted benzocyclic β-keto esters with amines: Selective reaction pathways depending on the nature of the amine radical cations

Photoinduced electron-transfer reaction of α-bromomethyl-substituted benzocyclic β-keto esters with tertiary amines was investigated. Debrominated β-keto esters and ring-expanded γ-keto esters were obtained as major products. On the basis of mechanistic experiments it was concluded that these products are formed via a reaction sequence of selective carbon-bromine bond cleavage and subsequent competitive hydrogen abstraction and Dowd-Beckwith ring-expansion of the resulting primary alkyl radicals. The characteristic product distribution observed for the type of amine used is rationalized on the basis of selective reaction pathways of generated radical intermediates that depend on the nature of the amine radical cations.

Photoreaction of halomethyl substituted benzocyclic ketones with amines: Radical cyclization and ring expansion reactions promoted through photoinduced electron transfer processes

Photoreaction of ethyl 2-bromomethyl-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 1a or other related compounds 1b-d with Me3SiCH2NEt2 in aqueous MeCN afforded ethyl 5-oxo-6,7,8,9-tetrahydrobenzocycloheptene-7-carboxylate 2a or corresponding ring expansion products 2a-d respectively.