22752-98-3

Basic information

• Product Name: 4-PYRIDYLPYRIDINIUM CHLORIDE
• Synonyms: 4-PYRIDYLPYRIDINIUM CHLORIDE;1-(4-pyridyl)pyridinium chloride;1,4'-Bipyridinium chloride;1,4'-Bipyridinium,chloride (1:1)
• CAS NO: 22752-98-3
• Molecular Formula: C₁₀H₉N₂*Cl
• Molecular Weight: 192.64486
• EINECS: 245-197-6
• Mol File: 22752-98-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 4-PYRIDYLPYRIDINIUM CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PYRIDYLPYRIDINIUM CHLORIDE(22752-98-3)
• EPA Substance Registry System: 4-PYRIDYLPYRIDINIUM CHLORIDE(22752-98-3)

Safety Data

• Hazardous Substances Data: 22752-98-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9N2.ClH/c1-2-8-12(9-3-1)10-4-6-11-7-5-10;/h1-9H;1H/q+1;/p-1

Upstream product

• 110-86-1 pyridine 
• 98-07-7 Benzotrichlorid 
• 123413-30-9 2,4-dimethylbenzotrichloride 
• 707-74-4 (trichloromethyl)mesitylene 

Downstream Products

• 4556-23-4 pyridine-4-thiol 
• 72358-71-5 4-<(4-fluorophenyl)amino>pyridine 
• 22961-45-1 N-phenylpyridin-4-amine 
• 25551-59-1 2-Nitro-N-(4'-pyridyl)aniline 
• 504-24-5 4-aminopyridine 
• 66571-30-0 1-γ-pyridylbenzotriazole 
• 25551-56-8 N-(3-nitrophenyl)-4-pyridinamine 
• 25551-60-4 N-(4-nitrophenyl)-4-pyridinamine 
• 80028-43-9 4-(p-(carboxyphenyl)amino)pyridine 
• 1020086-97-8 N-(4-nitrophenyl)-3-(4-pyridinylamino)benzamide 
• 60172-08-9 N₁-(4-pyridinyl)-1,4-benzenediamine 
• 23552-71-8 C₁₈H₁₄N₄O₃ 
• 1020086-91-2 C₁₉H₁₇N₄O₃⁽¹⁺⁾*Cl^(1-) 
• 32567-71-8 N-(4-nitrophenyl)-4-(4-pyridinylamino)benzamide 

Relevant articles and documents

AKT3 MODULATORS

Compounds of Formula la, lb, or Ic, (Ia); (Ib); or (Ic), are described, where the various substituents are defined herein. The compounds can modulate a property or effect of Akt3 in vitro or in vivo, and can also be used, individually or in combination with other agents, in the prevention or treatment of a variety of conditions. Methods for synthesizing the compounds are described. Pharmaceutical compositions and methods of using these compounds or compositions, individually or in combination with other agents or compositions, in the prevention or treatment of a variety of conditions are also described.

NATURE OF THE REDUCING AGENT AND MECHANISM OF THE REDUCTIVE CONDENSATION OF TRICHLOROMETHYLARENES WITH HYDROXYLAMINE AND HYDRAZINES IN PYRIDINE

It was shown that during the reductive condensation of trichloromethylarenes with hydroxylamine or hydrazines in pyridine the event of reduction with replacement of one chlorine atom by a hydrogen atom occurs without the participation of hydroxylamine or hydrazine.The first step of the reaction is the formation of N-(α,α-dichloroarylmethyl)pyridinium chlorides, which are converted by the action of the chloride anion or a second pyridine molecule to the corresponding 4-substituted 1,4-dihydropyridines.The latter undergo further aromatization with transfer of hydrogen from the 4-position of the dihydropyridine ring to the benzyl dichloromethylene group and the formation of N-(α-chloroarylmethyl)-4-chloropyridinium chlorides or N-(α-chloroarylmethyl)-4-(pyridino)pyridinium dichlorides, which give the corresponding aldehydes in hydrolysis or products of reductive condensation under the action of hydroxylamine or hydrazines.