22771-98-8

Basic information

• Product Name: Piperidine, 1-[(4-chlorophenyl)sulfonyl]-
• Synonyms: 1-<4-Chlorphenyl)sulfonyl>piperidin;N,N-Pentamethylen-4-chlorbenzol-sulfonamid;HMS539J17
• CAS NO: 22771-98-8
• Molecular Formula: C11H14ClNO2S
• Molecular Weight: 259.757
• Mol File: 22771-98-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Piperidine, 1-[(4-chlorophenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 1-[(4-chlorophenyl)sulfonyl]-(22771-98-8)
• EPA Substance Registry System: Piperidine, 1-[(4-chlorophenyl)sulfonyl]-(22771-98-8)

Safety Data

• Hazardous Substances Data: 22771-98-8(Hazardous Substances Data)

Upstream product

• 1679-18-1 4-Chlorophenylboronic acid 
• 110-89-4 piperidine 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 2591-86-8 N-Formylpiperidine 
• 106-54-7 p-Chlorothiophenol 
• 26971-85-7 p-Nitrophenyl p-chlorobenzenesulphonate 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 973-63-7 2,4-dinitrophenyl 4-chlorobenzenesulfonate 
• 155164-60-6 2-(4-chlorobenzenesulfonyl)-4,5-dichloropyridazin-3-one 

Relevant articles and documents

Iron-catalyzed synthesis of arylsulfinates through radical coupling reaction

A novel strategy for installation of a sulfonyl fragment into arenes has been accomplished via an iron-catalyzed radical coupling reaction. Arene radicals derived from diaryliodoniums via single electron transfer reaction combine with sulfoxylate anion radicals readily generated from commercially available rongalite (HOCH2SO2Na·2H2O) to afford arylsulfinates efficiently at room temperature. In this protocol, a broad range of functional groups are tolerated to give products in good yields.

Piperidinolysis of 4-Nitrophenyl X-Substituted benzenesulfonates and related compounds: Effect of changing leaving group and electrophilic center

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N-CYCLIC SULFONAMIDO INHIBITORS OF GAMMA SECRETASE

The invention provides N-cyclic sulfonamido compounds for use in treating or preventing cognitive disorders, such as Alzheimer’s Disease. Compounds of particular interest are defined by Formula (I), wherein R4, R5, R6, Rs