22774-39-6

Basic information

• Product Name: N,N-bis-cinnamylaniline
• Synonyms: N,N-bis-cinnamylaniline
• CAS NO: 22774-39-6
• Molecular Weight: 325.453
• Mol File: 22774-39-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N,N-bis-cinnamylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis-cinnamylaniline(22774-39-6)
• EPA Substance Registry System: N,N-bis-cinnamylaniline(22774-39-6)

Safety Data

• Hazardous Substances Data: 22774-39-6(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 2687-12-9 cinnamyl chloride 
• 104-54-1 3-Phenylpropenol 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 673-32-5 1-Phenylprop-1-yne 
• 4392-24-9 3-bromo-1-phenyl-1-propenyl bromide 
• 104-55-2 3-phenyl-propenal 

Downstream Products

• 1188022-73-2 2-(4-fluorophenyl)-4-phenylpyridine 
• 504413-43-8 2-(4-bromophenyl)-4-phenylpyridine 

Relevant articles and documents

Iron-Catalyzed Cyclization of Ketoxime Carboxylates and Tertiary Anilines for the Synthesis of Pyridines

A novel and efficient iron-catalyzed cyclization of ketoxime carboxylates and N,N-dialkylanilines for the modular synthesis of diverse pyridines was developed. The reaction was initiated by Fe-catalyzed N-O bond cleavage of ketoxime carboxylates in the presence of tertiary anilines. The methylene carbon on N,N-dialkylanilines functioned as a source of one-carbon synthon in the reaction. The reaction used readily available starting materials, tolerated various functional groups, and afforded 2,4-disubstituted and 2,4,6-trisubstituted pyridines in good to high yields under mild conditions.

Allylic amination of internal alkynes with aromatic and aliphatic amines using polymer-supported triphenylphosphane-palladium complex as a heterogeneous and recyclable catalyst

A facile and novel protocol for the allylic amination of internal alkynes with amines by using a polymer-supported triphenylphosphane-palladium complex [PS-TPP-Pd] as a highly active heterogeneous reusable catalyst was developed. The catalyst exhibited remarkable activity and is re-usable over five consecutive cycles. The protocol was applicable for a variety of hindered and functionalized aromatic/ aliphatic amines and afforded the desired allylic products in good to excellent yield.

Direct Reductive Amination of Aldehydes and Ketones Using Phenylsilane: Catalysis by Dibutyltin Dichloride

(matrix presented) A procedure for direct reductive amination of aldehydes and ketones was developed which uses phenylsilane as a stoichiometric reductant and dibutyltin dichloride as a catalyst. Suitable amines included anilines and dialkylamines but not monoalkylamines.