227776-28-5

Basic information

• Product Name: 4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER
• Synonyms: 4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER;4-[2-(1,3-Dihydro-1,3dioxo-2H-isoindol-yl)ethyl]-1-piperazinecarboxylic acid,1,1-dimethylethyl;tert-butyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethyl)piperazine-1-carboxylate;4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER
• CAS NO: 227776-28-5
• Molecular Formula: C19H25N3O4
• Molecular Weight: 359.42
• Mol File: 227776-28-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 489.5°Cat760mmHg
• Flash Point: 249.8°C
• Appearance: /
• Density: 1.231g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: 4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER(227776-28-5)
• EPA Substance Registry System: 4-[2-(1,3-DIHYDRO-1,3DIOXO-2H-ISOINDOL-YL)ETHYL]-1-PIPERAZINECARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER(227776-28-5)

Safety Data

• Hazardous Substances Data: 227776-28-5(Hazardous Substances Data)

Usage

Chemical Family

Piperazinecarboxylic acids

Molecular Structure

Contains a piperazine ring and a carboxylic acid group, with an ester functional group attached to the piperazine ring

Potential Pharmaceutical Applications

Due to its structural properties, it may interact with biological systems and have potential pharmaceutical uses.

Safety Precautions

Requires careful handling and storage in accordance with safety procedures to prevent potential hazards.

InChI:InChI=1/C19H25N3O4/c1-19(2,3)26-18(25)21-11-8-20(9-12-21)10-13-22-16(23)14-6-4-5-7-15(14)17(22)24/h4-7H,8-13H2,1-3H3

Upstream product

• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Downstream Products

• 192130-34-0 tert-butyl 4-(2-aminoethyl)piperazine-1-carboxylate 

Relevant articles and documents

PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST

Disclosed herein is a pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof useful as an A2A receptor antagonist, and a pharmaceutical composition comprising the same. Also disclosed herein is a method of treating cancer using the pyrazolotriazolopyrimidine derivative or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof as an A2A receptor antagonist.

CINNAMIC ACID AMIDE DERIVATIVE

The present invention provides a cinnamic acid amide derivative having an excellent analgesic action. The cinnamic acid amide derivative of the present invention is a compound showing excellent analgesic actions to not only a nociceptive pain model animal but also a neuropathic pain model animal, which is very useful as an agent for treating various pain diseases showing acute or chronic pains or neuropathic pains.

Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides

The invention relates to new piperazinyl-substituted pyridylalkane, alkene, and alkine acid amides substituted with saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group according to the general formula (I) as well as methods for the production of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.