22796-16-3

Basic information

• Product Name: 1-(tert-butyl)-4-(perfluoropropan-2-yl)benzene
• Synonyms: 1-(tert-butyl)-4-(perfluoropropan-2-yl)benzene
• CAS NO: 22796-16-3
• Molecular Weight: 302.235
• Mol File: 22796-16-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(tert-butyl)-4-(perfluoropropan-2-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(tert-butyl)-4-(perfluoropropan-2-yl)benzene(22796-16-3)
• EPA Substance Registry System: 1-(tert-butyl)-4-(perfluoropropan-2-yl)benzene(22796-16-3)

Safety Data

• Hazardous Substances Data: 22796-16-3(Hazardous Substances Data)

Upstream product

• 116-15-4 perfluoropropylene 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 87406-01-7 1,1,3,3,3-pentafluoro-2-<4-(1,1-dimethylethyl)phenyl>propene 
• 73471-97-3 1-(4-(tertbutyl)phenyl)-2,2,2-trifluoroethanone 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 22796-15-2 1,1,1,3,3,3-hexafluoro-2-(4-tert-butylphenyl)-2-propanol 

Relevant articles and documents

An I(I)/I(III) Catalysis Route to the Heptafluoroisopropyl Group: A Privileged Module in Contemporary Agrochemistry

The heptafluoroisopropyl group is emerging as a privileged chemotype in contemporary agrochemistry and features prominently in the current portfolio of leading insecticides. To reconcile the expansive potential of this module with the synthetic challenges

A hexafluoropropylene directly to the aryl borate method of oxidation heptafluoro isopropylation

The invention relates to a method for directly oxidizing arylboronic acid into heptafluoroisopropyl by utilizing hexafluoropropylene. The method comprises the following steps that silver fluoride is used as a fluorine source, under the effect of copper salt, the hexafluoropropylene and the arylboronic acid can be converted into a series of compounds containing heptafluoroisopropyl in organic solvents at the room temperature, and the reaction is also applicable to alkenylboronic acids. The method has the advantage that a series of compounds containing the heptafluoroisopropyl are synthesized through one-step reaction at high selectivity.