228107-17-3

Basic information

• Product Name: 2-Amino-4-phenylnaphthalene
• Synonyms: 2-Amino-4-phenylnaphthalene;3-aMino-1-phenylnaphthalene
• CAS NO: 228107-17-3
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 219.28112
• Mol File: 228107-17-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-4-phenylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-phenylnaphthalene(228107-17-3)
• EPA Substance Registry System: 2-Amino-4-phenylnaphthalene(228107-17-3)

Safety Data

• Hazardous Substances Data: 228107-17-3(Hazardous Substances Data)

Usage

Properties

Pale yellow solid at room temperature

Structure

Naphthalene core with an amino group and phenyl group attached at the 2 and 4 positions of the naphthalene ring

Uses

Precursor in synthesis of pharmaceuticals and dyes, potential applications in organic electronics and as a molecular probe in biological research

Safety precautions

Due to aromatic structure and potential health hazards, handle with caution and in accordance with proper safety protocols.

Upstream product

• 74924-94-0 4-bromonaphthalene-2-amine 
• 98-80-6 phenylboronic acid 
• 17560-24-6 1-phenylnaphthalene-3-carboxylic acid 

Relevant articles and documents

Aromaticity-Dependent Regioselectivity in Pd(II)-Catalyzed C-H Direct Arylation of Aryl Ureas

Palladium-catalyzed C-H direct arylation generally occurs on the ortho-position of directing groups. By comparing meta-arylated products of 2-naphthyl urea to ortho-arylated products of phenyl urea, the ortho- and meta-regioselectivity of aryl ureas were found to depend on the aromaticity of the corresponding aryl substituents. Thus, aromaticity is a new factor which can affect the regioselectivity in C-H direct arylation. The finding was further confirmed by regioselective direct arylation of indole and pyrrole derivatives.

Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors

Novel 5-HT3 receptor ligands were designed and synthesized with the aim of obtaining deeper insight into the molecular basis of the intrinsic efficacy of arylpiperazines interacting with the central 5-HT3 receptor. The newly synthesi