22813-58-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
N,N-DIMETHYL-4-CHLOROBUTANAMIDE is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals for its ability to contribute to the formation of desired active compounds in these products.
Used in Organic Synthesis:
In the realm of organic synthesis, N,N-DIMETHYL-4-CHLOROBUTANAMIDE serves as a solvent and reagent, facilitating various chemical reactions that are essential for the creation of complex organic molecules.
Used in Research and Development:
N,N-DIMETHYL-4-CHLOROBUTANAMIDE is also utilized in research and development settings, where its unique chemical properties are explored for potential applications in new chemical processes or as a component in innovative formulations.

InChI:InChI=1/C6H12ClNO/c1-8(2)6(9)4-3-5-7/h3-5H2,1-2H3

Upstream product

• 124-40-3 dimethyl amine 
• 4635-59-0 4-Chlorobutanoyl chloride 
• 3153-36-4 4-chloro-butyric acid ethyl ester 
• 84738-97-6 methylchloroaluminum N,N-dimethylamide 
• 122368-54-1 4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidine 
• 627-00-9 γ-chlorobutyric acid 

Downstream Products

• 129041-15-2 4-(N,N-Dibenzylamino)-N',N'-dimethylbutyramid 
• 115178-78-4 Benzoic acid 3-dimethylcarbamoyl-propyl ester 
• 67446-96-2 N-(3',4'-dichlorophenyl)-N-(4-dimethylaminobutyl)propionamide 

Relevant academic research and scientific papers

Cyclic Oxonium Salts: 13C Magnetic Resonance Spectroscopy. The Correlation of Chemical Shifts with the Calculated Charge Density

The 13C chemical shifts of several bicyclic and monocyclic oxonium salts are reported and, in the case of 5-membered ring unsaturated oxonium salts, compared with ab initio and CNDO calculated charges.A prime dependence of the 13C shielding on the ? charge delocalization effects induced by the Y group is established for the Y-substituted C-α carbon; a good correlation of δC-α vs q? is obtained, using ? bond-order terms.However, contradictory information arises from NMR and theoretical calculations for the C-ω carbon, which is distant from the Y group.The results are discussed.

4-[diaryl)hydroxymethyl]-1-piperidinealkylcarboxylic acids, salts and esters useful in the treatment of allergic disorders

Novel compounds useful in the treatment of allergic disorders and having the formula: STR1 where Ar and Ar1 are pyridinyl, phenyl, or substituted phenyl and where Y is --OH,--O? M≈ m,--O--loweralkyl, --O--Aryl, or NR1 R2 (R1, R2 =H, loweralkyl, aryl) are herein disclosed.

Piperdine and piperazine derivatives, and antihistaminic pharmaceutical compositions containing the same

Disclosed is a compound represented by Formula (I): STR1 wherein Ar1, Ar2, n, A, B and Z are as defined in claims. Disclosed are also a process for preparing the compound and pharmaceutical compositions containing the compound. The compound has an antihistamic and antiallergic effect.

AN ALTERNATIVE PROCEDURE FOR THE ALUMINUM-MEDIATED CONVERSION OF ESTERS TO AMIDES

A convenient method has been developed for directly converting esters to amides using reagents derived from the reaction of trimethylaluminum with ammonium chloride, methylamine hydrochloride or dimethylamine hydrochloride.