22815-63-0

Basic information

• Product Name: N-^t-butyl benzylcarbamate
• Synonyms: N-^t-butyl benzylcarbamate
• CAS NO: 22815-63-0
• Molecular Weight: 207.272
• Mol File: 22815-63-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-^t-butyl benzylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: N-^t-butyl benzylcarbamate(22815-63-0)
• EPA Substance Registry System: N-^t-butyl benzylcarbamate(22815-63-0)

Safety Data

• Hazardous Substances Data: 22815-63-0(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 75-98-9 Trimethylacetic acid 
• 124-38-9 carbon dioxide 
• 100-44-7 benzyl chloride 
• 75-64-9 tert-butylamine 
• 501-53-1 benzyl chloroformate 
• 754-10-9 2,2-dimethylpropionamide 
• 1609-86-5 Tert-butyl isocyanate 
• 75315-63-8 N-(benzyloxycarbonyl)succinimide 
• 69777-55-5 tert-butyl(morpholin-2-ylmethyl)carbamate 
• 119072-55-8 tert-butylisonitrile 
• 691-64-5 di-tert-butyl oxalate 
• 621-84-1 O-benzyl carbamate 
• 507-19-7 t-butyl bromide 

Downstream Products

• 15942-15-1 N-benzyl-N'-tert-butyl urea 
• 33553-82-1 4-chloro-1-phenyl-1-butanol 
• 126404-91-9 tert-Butyl-carbamic acid 2-hydroxy-1,2-diphenyl-ethyl ester 
• 126404-99-7 tert-Butyl-carbamic acid 1-methyl-1,2-diphenyl-ethyl ester 
• 126404-89-5 tert-Butyl-carbamic acid 5-chloro-1-phenyl-pentyl ester 
• 126404-95-3 tert-Butyl-carbamic acid 4-bromo-1-phenyl-pentyl ester 
• 126404-93-1 tert-Butyl-carbamic acid 2-hydroxy-4-iodo-3,3-dimethyl-1-phenyl-butyl ester 
• 126404-88-4 tert-Butyl-carbamic acid 4-chloro-1-phenyl-butyl ester 
• 126404-84-0 tert-Butyl-carbamic acid 1,2-diphenyl-ethyl ester 
• 126404-86-2 tert-Butyl-carbamic acid 3-chloromethyl-1-phenyl-but-3-enyl ester 
• 126405-01-4 tert-Butyl-carbamic acid 4-chloro-1-methyl-1-phenyl-butyl ester 
• 126404-87-3 tert-Butyl-carbamic acid (E)-5-chloro-1-phenyl-pent-3-enyl ester 
• 126404-98-6 tert-Butyl-carbamic acid 1-phenyl-1-trimethylsilanyl-ethyl ester 
• 126404-90-8 tert-Butyl-carbamic acid phenyl-trimethylsilanyl-methyl ester 

Relevant articles and documents

Zn- And Cu-catalyzed coupling of tertiary alkyl bromides and oxalates to forge challenging C?O, C?S, and C?N bonds

We describe here the facile construction of sterically hindered tertiary alkyl ethers and thioethers via the Zn(OTf)2catalyzed coupling of alcohols/phenols with unactivated tertiary alkyl bromides and the Cu(OTf)2-catalyzed thiolation of unactivated tertiary alkyl oxalates with thiols. The present protocol represents one of the most effective unactivated tertiary C(sp3)? heteroatom bond-forming conditions via readily accessible Lewis acid catalysis that is surprisingly less developed.

Oximes as reusable templates for the synthesis of ureas and carbamates by an: In situ generation of carbamoyl oximes

Oximes have been identified as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes under metal-free conditions. The recovered oxime has been utilised for three trials in the synthesis of urea derivatives without any loss in the yield and efficiency. In addition, this template approach could override the usage of hazardous and less stable isocyanates as substrates.

A high-yielding, expeditious, and multicomponent synthesis of urea and carbamate derivatives by using triphenylphosphine/trichloroisocyanuric acid system

An efficient method for the synthesis of urea and carbamate derivatives from amines and alcohols is described by using triphenylphosphine (PPh3)/trichloroisocyanuric acid system. The protocol allows for the preparation of symmetrical, unsymmetrical di, tri-, and tetra-substituted ureas and carbamates and is tolerant of a wide range of functional groups. To optimize the reaction conditions, experimental variables including temperature, the concentration of amine and alcohol, solvent, and reaction time were studied. Satisfactory yields were obtained at the optimized conditions. The present methodology is experimentally simple, mild, and represents a valuable alternative to the existing methods.