228399-13-1

Upstream product

• 228399-02-8 2,5-anhydro-3,6-di-O-benzoyl-4-O-methanesulfonyl-D-allose ethylene acetal 
• 157506-35-9 2,5-anhydro-3,6-di-O-methanesulfonyl-D-glucose ethylene acetal 
• 157506-37-1 2,5-anhydro-4,6-di-O-benzoyl-3-O-methanesulfonyl-D-glucose ethylene acetal 
• 98-88-4 benzoyl chloride 
• 258336-08-2 Benzoic acid (1R,2R,4R,5R)-4-[1,3]dioxolan-2-yl-3,6-dioxa-bicyclo[3.1.0]hex-2-ylmethyl ester 
• 228399-00-6 2,5-anhydro-3,6-di-O-benzoyl-D-allose ethylene acetal 
• 228399-06-2 C₂₃H₂₁F₃O₁₀S 

Downstream Products

• 360577-78-2 5-(3-azido-2,5-di-O-benzoyl-3-deoxy-β-D-xylofuranosyl)tetrazole 
• 410082-11-0 2,5-anhydro-4-azido-3,6-di-O-benzoyl-4-deoxy-D-gulononitrile 
• 410082-10-9 C₂₀H₁₈N₄O₆ 
• 615249-54-2 ethyl 2-(3-acetamido-2,5-di-O-benzoyl-3-deoxy-β-D-xylofuranosyl)thiazole-4-carboxylate 
• 615249-53-1 4-acetamido-2,5-anhydro-3,6-di-O-benzoyl-4-deoxy-D-gulono-thioamide 
• 615249-52-0 (3-acetamido-2,5-di-O-benzoyl-3-deoxy-β-D-xylofuranosyl)cyanide 
• 615249-51-9 C₂₂H₂₂N₂O₇ 
• 615249-50-8 C₂₂H₂₁NO₇ 
• 914983-65-6 2,5-anhydro-3,6-di-O-benzoyl-4-deoxy-4-trifluoroacetamido-D-gulose ethylene acetal 
• 914983-69-0 2,5-anhydro-3,6-di-O-benzoyl-4-deoxy-4-trifluoroacetamido-D-gulono-thioamide 
• 914983-67-8 C₂₂H₁₉F₃N₂O₇ 
• 914983-68-9 (2,5-di-O-benzoyl-3-deoxy-3-trifluoroacetamido-β-D-xylofuranosyl)cyanide 
• 914983-66-7 C₂₂H₁₈F₃NO₇ 
• 615249-48-4 2,5-anhydro-4-acetamido-3,6-di-O-benzoyl-4-deoxy-D-gulose ethylene acetal 

Relevant academic research and scientific papers

Structure based design, synthesis and in vitro antitumour activity of tiazofurin stereoisomers with nitrogen functions at the C-2′ or C-3′ positions

Three novel tiazofurin analogues having D-arabino stereochemistry and nitrogen functionalities at the C-2′ position (5–7) have been designed and synthesized in multistep sequences, starting from D-glucose. The known D-xylo stereoisomer of 1 (compound 2) a

2-(3-Amino-3-deoxy-β-d-xylofuranosyl)thiazole-4-carboxamide: A new tiazofurin analogue with potent antitumour activity

A new tiazofurin analogue, 2-(3-amino-3-deoxy-β-d-xylofuranosyl)thiazole-4-carboxamide (3), was synthesized starting from d-glucose and evaluated for its in vitro antiproliferative activity against a panel of human tumour cell lines. Compound 3 exhibited

De novo synthesis of two new cytotoxic tiazofurin analogues with modified sugar moieties

A divergent synthesis of two novel tiazofurin analogues, 2-(3-deoxy-3-fluoro-β-D-xylofuranosyl)thiazole-4-carboxamide (2) and 2-(3-acetamido-3-deoxy-β-D-xylofuranosyl)thiazole-4-carboxamide (3), has been achieved starting from D-glucose. Both nucleoside a

Synthesis and biological evaluation of new pyrazole- and tetrazole-related C-nucleosides with modified sugar moieties

3(5)-Carboxamido-4-(β-D-ribofuranosyl)pyrazoles bearing 2′-benzamido (15) and 3′-mesyloxy (29) isosteric groups, as well as the tetrazole C-nucleosides with 2-benzamido-2-deoxy-β-D-ribofuranose (19) and 3-azido-3-deoxy-β-D-xylofuranose (36) as sugar segments, have been synthesized starting from D-glucose, by utilizing the 2,5-anhydro-D-glucose ethylene acetal derivatives 1 and 20 as divergent intermediates. The C-nucleosides 15 and 36 were shown to be moderate inhibitors of the in vitro growth of both N2a and BHK 21 tumour cell lines, whereas 29 showed a selective, although not potent cytotoxic activity against N2a cells. Compound 29 also showed a moderate in vitro antiviral activity towards the rabies virus.