914983-68-9Relevant academic research and scientific papers
Structure based design, synthesis and in vitro antitumour activity of tiazofurin stereoisomers with nitrogen functions at the C-2′ or C-3′ positions
Koji?, Vesna,Popsavin, Mirjana,Spai?, Sa?a,Jakimov, Dimitar,Kova?evi?, Ivana,Svir?ev, Milo?,Aleksi?, Lidija,Zelenovi?, Bojana Sre?o,Popsavin, Velimir
, (2019/09/30)
Three novel tiazofurin analogues having D-arabino stereochemistry and nitrogen functionalities at the C-2′ position (5–7) have been designed and synthesized in multistep sequences, starting from D-glucose. The known D-xylo stereoisomer of 1 (compound 2) a
2-(3-Amino-3-deoxy-β-d-xylofuranosyl)thiazole-4-carboxamide: A new tiazofurin analogue with potent antitumour activity
Popsavin, Mirjana,Spaic, Sasa,Svircev, Milos,Kojic, Vesna,Bogdanovic, Gordana,Popsavin, Velimir
, p. 5317 - 5320 (2007/10/03)
A new tiazofurin analogue, 2-(3-amino-3-deoxy-β-d-xylofuranosyl)thiazole-4-carboxamide (3), was synthesized starting from d-glucose and evaluated for its in vitro antiproliferative activity against a panel of human tumour cell lines. Compound 3 exhibited
