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CAS

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2284-32-4

Estriol triacetate is a synthetic estrogen hormone derived from the natural hormone estriol. It is formulated as a triacetate to enhance absorption and prolong its effects in the body. This medication works by binding to estrogen receptors, increasing estrogen levels, and alleviating menopausal symptoms such as hot flashes, vaginal dryness, and mood changes. Estriol triacetate is available in various dosage forms, including oral tablets and topical creams, and is generally well-tolerated with minimal side effects when used as directed by a healthcare professional.

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  • 2284-32-4 Structure

  • Basic information

    1. Product Name: ESTRIOL TRIACETATE
    2. Synonyms: ESTRIOL TRIACETATE;1,3,5(10)-ESTRATRIEN-3,16-ALPHA, 17-BETA-TRIOL TRIACETATE;1,3,5(10)-ESTRATRIEN-3,16ALPHA,17BETA-TRIOL 3,16,17-TRIACETATE;estra-1,3,5(10)-triene-3,16-alpha,17-beta-triol,triacetate(ester);oestrioltriacetate;Estra-1,3,5(10)-triene-3,16α,17β-triol triacetate;[(17R)-3,16-diacetyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] acetate;[(17R)-3,16-diacetyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] ethanoate
    3. CAS NO:2284-32-4
    4. Molecular Formula: C24H30O6
    5. Molecular Weight: 414.49
    6. EINECS: N/A
    7. Product Categories: Steroids
    8. Mol File: 2284-32-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 509.5°Cat760mmHg
    3. Flash Point: 218.9°C
    4. Appearance: /
    5. Density: 1.22g/cm3
    6. Vapor Pressure: 1.69E-10mmHg at 25°C
    7. Refractive Index: 1.558
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: ESTRIOL TRIACETATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: ESTRIOL TRIACETATE(2284-32-4)
    12. EPA Substance Registry System: ESTRIOL TRIACETATE(2284-32-4)

  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 20/21/22-40
    3. Safety Statements: 22-36
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2284-32-4(Hazardous Substances Data)

2284-32-4 Usage

Uses

Used in Menopause Treatment:
Estriol triacetate is used as a hormone replacement therapy for the treatment of menopausal symptoms. It helps to alleviate symptoms such as hot flashes, vaginal dryness, and mood changes by increasing estrogen levels in the body.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, estriol triacetate is used as an active ingredient in medications designed to treat menopausal symptoms. It is formulated into various dosage forms, such as oral tablets and topical creams, to provide effective relief to women experiencing menopause.
Used in Hormone Replacement Therapy:
Estriol triacetate is used as a component in hormone replacement therapy, which aims to restore hormonal balance in women experiencing menopause. By binding to estrogen receptors and increasing estrogen levels, it helps to alleviate the symptoms associated with hormonal fluctuations during this stage of life.

Check Digit Verification of cas no

The CAS Registry Mumber 2284-32-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,8 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2284-32:
(6*2)+(5*2)+(4*8)+(3*4)+(2*3)+(1*2)=74
74 % 10 = 4
So 2284-32-4 is a valid CAS Registry Number.
InChI:InChI=1/C24H30O6/c1-13(25)28-17-6-8-18-16(11-17)5-7-20-19(18)9-10-24(4)21(20)12-22(29-14(2)26)23(24)30-15(3)27/h6,8,11,19-23H,5,7,9-10,12H2,1-4H3/t19?,20?,21?,22?,23-,24?/m0/s1

2284-32-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,16α,17β-estriol triacetate

1.2 Other means of identification

Product number -
Other names 1,3,5(10)-ESTRATRIEN-3,16-ALPHA,17-BETA-TRIOL TRIACETATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2284-32-4 SDS

2284-32-4Relevant articles and documents

Synthesis of 6α-functionalized estriol haptens and protein conjugates thereof

-

, (2008/06/13)

Disclosed are 6α-derivatized estriol compounds which, when conjugated to a protein, are useful in the in vivo preparation of antibodies specific to estriol. When labeled with a detectable label, the estriol derivatives are useful as haptens in a competitive immunoassay for estriol which demonstrate superior sensitivity with respect to estriol specific antibodies.

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