1474-53-9 Usage
Uses
Used in Pharmaceutical Industry:
17-BETA-ESTRADIOL 3-METHYL ETHER is used as a pharmaceutical compound for its anti-proliferative effects on estrogen receptor-negative breast cancer cells. It functions as a GPR3 antagonist, which helps in inhibiting the growth and proliferation of cancer cells.
Used in Cancer Research:
In the field of cancer research, 17-BETA-ESTRADIOL 3-METHYL ETHER is utilized as a potential therapeutic agent for estrogen receptor-negative breast cancer. Its role as a GPR3 antagonist makes it a valuable candidate for further investigation into its potential applications in cancer treatment and prevention.
Used in Drug Development:
17-BETA-ESTRADIOL 3-METHYL ETHER is also used in the development of new drugs targeting estrogen receptor-negative breast cancer. Its unique properties and interactions with cancer cells make it a promising candidate for the creation of novel therapeutic strategies and drug formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 1474-53-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,7 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1474-53:
(6*1)+(5*4)+(4*7)+(3*4)+(2*5)+(1*3)=79
79 % 10 = 9
So 1474-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O3/c1-19-8-7-14-13-6-4-12(22-2)9-11(13)3-5-15(14)16(19)10-17(20)18(19)21/h4,6,9,14-18,20-21H,3,5,7-8,10H2,1-2H3/t14?,15?,16?,17-,18?,19?/m1/s1
1474-53-9Relevant articles and documents
Rearrangement and fragmentation of estrogen ether ions: New aspects found with Fourier transform ion cyclotron resonance mass spectrometry
Freudenhammer, Christoph,Grotemeyer, Juergen
experimental part, p. 489 - 501 (2011/10/31)
Electrospray ionization mass spectra of several di- and tri-hydroxy-estratriene-ethers, as well as estradiol and estriol, have been investigated by high-resolution mass spectrometry. The fragmentation mechanisms leading to the loss of water molecules from the protonated molecular ion have been rationalized by using protecting groups as well as mass spectrometric means such as collision-induced dissociation and infrared multi-photon dissociation. The unexpected observation of a simultaneous loss of two water molecules from the protonated estradiol ethers and of three water molecules from the protonated estriol ethers has been discussed with respect to varying reaction mechanisms and rearrangements. Results and conclusions derived from them were obtained by adequate deuterated ethers.
