228418-95-9Relevant academic research and scientific papers
Metal-free oxidative direct C(sp3)-H bond functionalization of ethers with α,α-diaryl allylic alcohols
Chu, Xue-Qiang,Meng, Hua,Zi, You,Xu, Xiao-Ping,Ji, Shun-Jun
supporting information, p. 9718 - 9721 (2014/08/18)
A metal-free method for direct C(sp3)-H bond functionalization of simple ethers with α,α-diaryl allylic alcohols is described. The established protocol provides facile access to α-aryl-β-oxyalkylated carbonyl ketones via radical addition and a
Arylpiperazines having activity at the serotonin 1A receptor
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, (2008/06/13)
A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
Pyrrolidine and pyrroline derivatives having effects on serotonin related systems
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Page column 40, (2010/02/05)
The present invention provides the compounds of the following formula (I): and a method for inhibiting the reuptake of seretonin, antagonizing the 5-HT1Areceptor and antagonizing the 5-HT2Areceptor which comprises administering to a subject in need of such treatment an effective amount of formula (I).
Piperidine derivatives having effects on serotonin related systems
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, (2008/06/13)
The present invention provides the compounds of the following formula: Wherein the variables are as defined in the specification and a method for inhibiting the reuptake of seretonin, antagonizing the 5-HT1Areceptor and antagonizing the 5-HT2Areceptor which comprises administering to a subject in need of such treatment an effective amount of the compound of above formula.
Azepine derivatives having effects on serotonin related systems
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, (2008/06/13)
The present invention provides compounds of formula I and a method of inhibiting the reuptake of serotonin, antagonizing the 5-HT1Areceptor and antagonizing the 5-HT2Areceptor which comprises administering to a subject in need of suc
Arylpiperazines having activity at the serotonin 1A receptor
-
, (2008/06/13)
A series of aryl piperazine compounds of the formula: or the pharmaceutically acceptable salts thereof, are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1Areceptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
