228422-24-0Relevant academic research and scientific papers
Precursors for the production of chiral 1,3-aminoalcohols
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, (2008/06/13)
The disclosure describes novel precursors for the preparation of chiral 1,3-aminoalcohols. The precursors are chiral 4-hydroxycarboxamides, 4-hydroxyhydroxamic acids, or 4-hydroxyhydrazides produced from chiral gamma-lactones, which in turn are derived from 1,4-diols by stereoselective oxidation. The chiral 4-hydroxycarboxamides, 4-hydroxyhydroxamic acids, or 4-hydroxyhydrazides are converted into chiral 1,3-aminoalcohols by stereospecific rearrangement.
Synthesis and biological activity of some 2-aminopurine carbonucleosides
Santana,Teijeira,Uriarte,Teran,Andrei,Snoeck,De Clercq
, p. 1337 - 1339 (2007/10/03)
A series of new one two substituted carbonucleoside analogues (OTC) of purine was synthesized and evaluated against cytomegalovirus and varicella- zoster virus in human embryonic lung (HEL) cells.
