22845-55-2Relevant articles and documents
An ortho-quinodimethane route to Lasofoxifene and U23469
Yoshida, Hiroto,Yoshida, Ryuma,Mukae, Masashi,Ohshita, Joji,Takaki, Ken
, p. 1272 - 1274 (2015/09/22)
Lasofoxifene, a third-generation selective estrogen receptor modulator, could be synthesized via regio-and stereoselective [4 + 2] cycloaddition between an ortho-quinodimethane and a borylalkene. This protocol was also applicable to the synthesis of antie