2286-33-1

Basic information

• Product Name: Ethyl (2E)-2-cyano-3-(4-nitrophenyl)-2-propenoate
• Synonyms: Ethyl (2E)-2-cyano-3-(4-nitrophenyl)-2-propenoate;Ethyl 2-Cyano-3-(4-nitrophenyl)
• CAS NO: 2286-33-1
• Molecular Formula: C₁₂H₁₀N₂O₄
• Molecular Weight: 246.22
• Mol File: 2286-33-1.mol
• Article Data: 111

Chemical Properties

• Boiling Point: 385.8°Cat760mmHg
• Flash Point: 187.1°C
• Appearance: /
• Density: 1.306g/cm³
• Vapor Pressure: 3.72E-06mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: Ethyl (2E)-2-cyano-3-(4-nitrophenyl)-2-propenoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl (2E)-2-cyano-3-(4-nitrophenyl)-2-propenoate(2286-33-1)
• EPA Substance Registry System: Ethyl (2E)-2-cyano-3-(4-nitrophenyl)-2-propenoate(2286-33-1)

Safety Data

• Hazardous Substances Data: 2286-33-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H10N2O4/c1-2-18-12(15)10(8-13)7-9-3-5-11(6-4-9)14(16)17/h3-7H,2H2,1H3/b10-7-

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 105-56-6 ethyl 2-cyanoacetate 
• 52906-63-5 2-cyano-3-(4-nitrophenyl)propionic acid ethyl ester 
• 881-67-4 4-nitrobenzaldehyde dimethyl acetal 
• 619-73-8 4-nitrobenzyl chloride 
• 64-17-5 ethanol 
• 105-34-0 methyl 2-cyanoacetate 
• 100-19-6 (4-nitrophenyl)ethanone 
• 86268-44-2 Cyano-(tri-p-tolyl-λ⁵-arsanylidene)-acetic acid ethyl ester 
• 143490-05-5 Cyano-(triphenyl-λ⁵-arsanylidene)-acetic acid ethyl ester 
• 60951-74-8 2-cyano-3-(4'-nitro-1'-phenyl)acrylic acid 

Downstream Products

• 62966-27-2 1-Cyano-2,2,3,3-tetramethoxy-4-(4-nitro-phenyl)-cyclobutanecarboxylic acid ethyl ester 
• 65576-64-9 5-amino-2-(4-nitro-benzylidene)-7-(4-nitro-phenyl)-3-oxo-2,3-dihydro-7H-thiazolo[3,2-a]pyridine-6,8-dicarboxylic acid diethyl ester 
• 37428-90-3 (5Z)-5-(4-nitro-benzylidene)-2-thioxo-imidazolidin-4-one 
• 62089-28-5 5-(4-nitrophenyl)-1-phenyl-1H-pyrazole 
• 30980-77-9 ethyl 3-(4-aminophenyl)-2-cyanoacrylate 
• 35768-28-6 2-cyano-3-(4-nitro-phenyl)-oxiranecarboxylic acid ethyl ester 

Relevant articles and documents

Highly Active Copper(I)-Chalcogenone Catalyzed Knoevenagel Condensation Reaction Using Various Aldehydes and Active Methylene Compounds

First copper(I) chalcogenones catalysed Knoevenagel Condensation reactions have been reported. No illustration of the utilization of this copper-chalcogenone complex class in Knoevenagel Condensation catalysis can be found. Thus, copper(I) bis(benzimidazole-2-chalcogenone) catalysts [Cu(L1)4]+BF4? (1) and [Cu(L2)4]+BF4? (2) (L1 = bis(1-isopropyl-benzimidazole-2-selone)-3-ethyl; L2 = bis(1-isopropyl-benzimidazole-2-thione)-3-ethyl) have been utilized as catalysts in the Knoevenagel Condensation reactions. These copper(I) chalcogenone catalysts have shown high efficiency for the catalytic Knoevenagel Condensation of aryl aldehydes and active methylene compounds. In particular, complex 2, exhibit the best catalytic activities. The scope of the catalytic reactions has been investigated with 22 different molecules. The excellent catalytic activity has been depicted for various types of substrates with either electron-rich or deficient aryl aldehydes. The present investigation features relatively mild reaction conditions with good functional group tolerance and excellent yields. Graphic Abstract: The first copper(I)-chalcogenone complexes catalysed Knoevenagel Condensation reactions?have also been investigated, and revealed the best catalytic activities. [Figure not available: see fulltext.]

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