22868-29-7

Basic information

• Product Name: 2-(3-chlorophenyl)-1,3-benzoxazole
• Synonyms: 2-(3-chlorophenyl)-1,3-benzoxazole
• CAS NO: 22868-29-7
• Molecular Formula: C₁₃H₈ClNO
• Molecular Weight: 229.66172
• Mol File: 22868-29-7.mol
• Article Data: 35

Chemical Properties

• Melting Point: 124-125 °C
• Boiling Point: 333.6°Cat760mmHg
• Flash Point: 155.5°C
• Appearance: /
• Density: 1.298g/cm³
• Vapor Pressure: 0.000262mmHg at 25°C
• Refractive Index: 1.643
• PKA: 0.93±0.10(Predicted)
• CAS DataBase Reference: 2-(3-chlorophenyl)-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chlorophenyl)-1,3-benzoxazole(22868-29-7)
• EPA Substance Registry System: 2-(3-chlorophenyl)-1,3-benzoxazole(22868-29-7)

Safety Data

• Hazardous Substances Data: 22868-29-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H8ClNO/c14-10-5-3-4-9(8-10)13-15-11-6-1-2-7-12(11)16-13/h1-8H

Upstream product

• 618-46-2 m-Chlorobenzoyl chloride 
• 95-55-6 2-amino-phenol 
• 6266-10-0 2-[(2-chlorobenzylidene)amino]phenol 
• 321-31-3 1-(3-chlorophenyl)-2,2,2-trifluoroethanone 
• 273-53-0 benzoxazole 
• 4152-90-3 m-chlorobenzylamine 
• 535-80-8 3-chlorobenzoate 
• 108-37-2 1-bromo-3-chlorobenzene 
• 349611-65-0 C₁₃H₉BrClNO 
• 13028-89-2 3-chlorobenzylidene-2-aminophenol 
• 620-20-2 1-Chloro-3-chloromethyl-benzene 
• 873-63-2 m-chlorobenzyl alcohol 
• 64648-18-6 N-methoxy(m-chloro)benzamide 
• 349128-35-4 3-chloro-N-(2-iodophenyl)benzamide 

Downstream Products

• 1042719-83-4 2-(2-phenyl-5-chlorophenyl)-1,3-benzoxazole 
• 1042719-85-6 2-[2-(3-bromophenyl)-5-chlorophenyl]-1,3-benzoxazole 
• 1042719-84-5 2-[2-(4-methylphenyl)-5-chlorophenyl]-1,3-benzoxazole 
• 1315571-15-3 6-chloro-2-(3-chlorophenyl)benzoxazole 
• 51589-62-9 2-(2'-Hydroxy-5'-chlorophenyl)benzoxazole 
• 1415419-79-2 2-[5-chloro-2-(4-chlorobenzoyl)phenyl]benzoxazole 
• 1226014-86-3 6-bromo-2-(3-chlorophenyl)benzoxazole 
• 1325241-82-4 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(3-chlorophenyl)benzoxazole 

Relevant articles and documents

Synthesis, Characterization and DFT-D Studies of 2-Aminoethoxycalix[4]resorcinarenes: A Novel Heterogeneous Organocatalyst

The present article reports the synthesis of two novel supramolecular architectures, Phenyl(octa-2-aminoethoxy)calix[4]resorcinarene and 2-Aminoethoxyphenyl-(octa-2-aminoethoxy)calix[4]resorcinarene via surface functionalization and describes their applic

TEMPO-mediated aerobic oxidative synthesis of 2-aryl benzoxazoles via ring-opening of benzoxazoles with benzylamines

A simple and efficient TEMPO-mediated system for aerobic oxidative synthesis of 2-aryl benzoxazoles from readily available benzoxazoles and primary benzylic and hetero benzylic amines is presented in one pot. The reaction proceeds through the ring-opening of benzoxazoles and is followed by oxidative condensation with benzylamines. These metal-free, straightforward reactions worked well with a wide range of substrates, yielding moderate to good yields under mild conditions using air as an external green oxidant.

Syntheses, characterization, and catalytic potential of novel vanadium and molybdenum Schiff base complexes for the preparation of benzimidazoles, benzoxazoles, and benzothiazoles under thermal and ultrasonic conditions

A new ONO-tridentate Schiff base ligand (H2L) derived from 3-methoxysalicylaldehyde and nicotinic hydrazide was synthesized and characterized by elemental analysis, FT-IR, 1H NMR, 13C NMR, UV–Vis, and powder XRD studies. Then, oxovanadium(V) and dioxomolybdenum(VI) Schiff base complexes, VOL and MoO2L, were also prepared and characterized by different techniques. Moreover, the catalytic activities of both complexes were investigated for the synthesis of benzimidazoles, benzoxazoles, and benzothiazoles under reflux conditions as well as through ultrasonic irradiation. The results revealed several advantages of this procedure, including high product yields, short reaction times, facile work-up procedure, simplicity in operation, eco-friendly reaction conditions, and green aspects by avoiding toxic catalysts and solvents. Graphic abstract: [Figure not available: see fulltext.]